Evidence map›Paper›PMID 32597759›Full record

ArticleeLife2020

CARD14

Joan Manils, Louise V Webb, Ashleigh Howes, Julia Janzen, Stefan Boeing, Anne M Bowcock, Steven C Ley

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Psoriasis-like disease prevents squamous skin tumor development by neutrophil-driven inflammation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  9. Article
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  11. JID innovations : skin science from molecules to population health · 2023
    Article
  12. Article
  13. Article
  14. Immune responses and therapeutic options in psoriasis.Cellular and molecular life sciences : CMLS · 2021
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Joan Manils *The Francis Crick Institute, London, United Kingdom.ORCID 0000-0001-8429-1295
Louise V Webb *The Francis Crick Institute, London, United Kingdom.
Ashleigh HowesNational Heart & Lung Institute, Imperial College London, London, United Kingdom.
Julia JanzenDepartment of Immunology & Inflammation, Imperial College London, London, United Kingdom.
Stefan BoeingThe Francis Crick Institute, London, United Kingdom.
Anne M BowcockNational Heart & Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0001-8691-9090
Steven C LeyDepartment of Immunology & Inflammation, Imperial College London, London, United Kingdom.ORCID 0000-0001-5911-9223
Imperial College London · GBThe Francis Crick Institute · GB

Funding

British Heart Foundation PG/15/57/31580Cancer Research UK FC001103Medical Research Council FC001103National Psoriasis Foundation WMIS_P74088NIH HHS R01AR05026Wellcome Trust FC001103
6 · The paper itself

Abstract

To investigate how the

Indexed as

MutationAnimalsCARD Signaling Adaptor ProteinsDermatitisFemaleGuanylate KinasesMaleMicePsoriasisSystemic Inflammatory Response SyndromeTumor Necrosis Factor-alphaCard14 protein, mouseCARD Signaling Adaptor ProteinsGuanylate KinasesTumor Necrosis Factor-alphaCARD14immunologyinflammationkeratinocytesmousenf-kbpsoriasisTNF

Identifiers

PMID32597759
PMCPMC7351492
OpenAlexW3037606264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.