ArticleMagnetic resonance in medicine2020
High-sensitivity CEST mapping using a spatiotemporal correlation-enhanced method.
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- MixBranchNet: a task-adaptive network for glioma segmentation and genotype prediction by exploiting spatial-spectral correlations in CEST MRI.Frontiers in oncology · 2026Article
- Toward quantitative CEST imaging of glutamate in the mouse brain using a multi-pool exchange model calibrated byMagnetic resonance in medicine · 2025Article
- Mitochondrial oxidative phosphorylation capacity in skeletal muscle measured by ultrafast Z-spectroscopy (UFZ) MRI at 3T.Magnetic resonance in medicine · 2025Article
- Elucidating metabolite and pH variations in stroke through guanidino, amine and amide CEST MRI: A comparative multi-field study at 9.4T and 3T.NeuroImage · 2025Article
- Single-shot multiparametric MRI for separatingTheranostics · 2025Article
- Whole-cerebrum guanidino and amide CEST mapping at 3 T by a 3D stack-of-spirals gradient echo acquisition.Magnetic resonance in medicine · 2024Article
- Development and Validation of Four Different Methods to Improve MRI-CEST Tumor pH Mapping in Presence of Fat.Journal of imaging · 2024Article
- A Denoising Convolutional Autoencoder for SNR Enhancement in Chemical Exchange Saturation Transfer imaging: (DCAE-CEST).bioRxiv : the preprint server for biology · 2024Article
- Specific and rapid guanidinium CEST imaging using double saturation power and QUASS analysis in a rodent model of global ischemia.Magnetic resonance in medicine · 2024Article
- Simultaneous creatine and phosphocreatine mapping of skeletal muscle by CEST MRI at 3T.Magnetic resonance in medicine · 2024Article
- Creatine mapping of the brain at 3T by CEST MRI.Magnetic resonance in medicine · 2024Article
- Deep Learning-Based Denoising of CEST MR Data: A Feasibility Study on Applying Synthetic Phantoms in Medical Imaging.Diagnostics (Basel, Switzerland) · 2023Article
- Longitudinal multiparametric MRI of traumatic spinal cord injury in animal models.Magnetic resonance imaging · 2023Review
- Isolation of amide proton transfer effect and relayed nuclear Overhauser enhancement effect at -3.5ppm using CEST with double saturation powers.Magnetic resonance in medicine · 2023Article
- Multiparametric chemical exchange saturation transfer MRI detects metabolic changes in breast cancer following immunotherapy.Journal of translational medicine · 2023Article
- The exchange rate of creatine CEST in mouse brain.Magnetic resonance in medicine · 2023Article
- Chemical exchange saturation transfer imaging of creatine, phosphocreatine, and protein arginine residue in tissues.NMR in biomedicine · 2023Review
- Guanidinium and amide CEST mapping of human brain by high spectral resolution CEST at 3 T.Magnetic resonance in medicine · 2023Article
- Whole-brain steady-state CEST at 3 T using MR Multitasking.Magnetic resonance in medicine · 2022Article
- A Multimodal MR Imaging Study of the Effect of Hippocampal Damage on Affective and Cognitive Functions in a Rat Model of Chronic Exposure to a Plateau Environment.Neurochemical research · 2022Article
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5 authors.
Funding
Abstract
purposeTo obtain high-sensitivity CEST maps by exploiting the spatiotemporal correlation between CEST images.
methodsA postprocessing method accomplished by multilinear singular value decomposition (MLSVD) was used to enhance the CEST SNR by exploiting the correlation between the Z-spectrum for each voxel and the low-rank property of the overall CEST data. The performance of this method was evaluated using CrCEST in ischemic mouse brain at 11.7 tesla. Then, MLSVD CEST was applied to obtain Cr, amide, and amine CEST maps of the ischemic mouse brain to demonstrate its general applications.
resultsComplex-valued Gaussian noise was added to CEST k-space data to mimic a low SNR situation. MLSVD CEST analysis was able to suppress the noise, recover the degraded CEST peak, and provide better CrCEST quality compared to the smoothing and singular value decomposition (SVD)-based denoising methods. High-resolution Cr, amide, and amine CEST maps of an ischemic stroke using MLSVD CEST suggest that CrCEST is also a sensitive pH mapping method, and a wide range of pH changes can be detected by combing CrCEST with amine CEST at high magnetic fields.
conclusionMLSVD CEST provides a simple and efficient way to improve the SNR of CEST images.
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