Evidence map›Paper›PMID 32597247›Full record

ArticleDrug delivery2020

Enhanced anti-hepatoma effect of a novel curcumin analog C086

Yanping Deng, Chun Chen, Zhifeng Xiao, Xiuwang Huang, Jianhua Xu

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yanping DengThe School of Pharmacy, Fujian Medical University, Fuzhou, China.
Chun ChenThe School of Pharmacy, Fujian Medical University, Fuzhou, China.
Zhifeng XiaoThe School of Pharmacy, Fujian Medical University, Fuzhou, China.
Xiuwang HuangPublic Technology Center, Fujian Medical University, Fuzhou, China.
Jianhua XuThe School of Pharmacy, Fujian Medical University, Fuzhou, China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel curcumin analog C086, previously identified as an oral novel heat shock protein 90 (Hsp90) inhibitor, was found to exhibit anti-hepatoma activity

Indexed as

AnimalsAntineoplastic AgentsCalorimetry, Differential ScanningCarcinoma, HepatocellularCell Line, TumorCurcuminDrug StabilityHSP90 Heat-Shock ProteinsLiver NeoplasmsMaleMiceMice, Inbred BALB CMice, NudeRatsRats, Sprague-DawleySolubilityAntineoplastic AgentsCurcumincurcumin analog C086HSP90 Heat-Shock Proteinsanti-hepatomaCurcumin analog C086in vivo bioavailabilityliver accumulationsolid dispersion

Identifiers

PMID32597247
PMCPMC8216446
OpenAlexW3037702838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.