ArticlePsycho-oncology2020
Self-reported cognitive outcomes among adolescent and young adult patients with noncentral nervous system cancers.
Article in Psycho-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Mapping self-awareness of cancer-related cognitive impairment: a scoping review of evidence, methods, and neurobiological correlates.Frontiers in neurology · 2025Pooled it
- Cognitive complaints and their associations with role functioning limitations among adolescent and young adult cancer survivors in Hong Kong.Asia-Pacific journal of oncology nursing · 2026Article
- Observational
- Assessment of Psychological Distress Among Indian Adolescents and Young Adults with Solid Cancer Using the National Comprehensive Cancer Network Distress Thermometer.South Asian journal of cancer · 2025Article
- Educational and occupational aspirations of adolescent and young adult cancer survivors: a qualitative analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Psychological Outcomes in Adolescent and Young Adult Cancer Survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Review
- Current investigation of neurocognitive functioning in preschool children with cancer: A cross-sectional study from western China.PloS one · 2024Article
- Cancer-related cognitive impairment in racial and ethnic minority groups: a scoping review.Journal of cancer research and clinical oncology · 2023Article
- Brain-derived neurotrophic factor as a biomarker in cancer-related cognitive impairment among adolescent and young adult cancer patients.Scientific reports · 2023Article
- Health-related quality of life in adolescents and young adults with and without cancer, using propensity score matching.Journal of cancer survivorship : research and practice · 2023Article
- Neurocognitive function and health-related quality of life in a nationwide cohort of long-term childhood brain tumor survivors.Neuro-oncology practice · 2023Article
- Substance Use Among Young Adult Survivors of Childhood Cancer With Cognitive Impairment: An Analysis of the Project Forward Cohort.JCO oncology practice · 2023Article
- Cognitive impairment in adolescent and young adult cancer patients: Pre-treatment findings of a longitudinal study.Cancer medicine · 2023Article
- Work ability and cognitive impairments in young adult cancer patients: associated factors and changes over time-results from the AYA-Leipzig study.Journal of cancer survivorship : research and practice · 2022Article
- Feasibility of Cognitive Training to Promote Recovery in Cancer-Related Cognitive Impairment in Adolescent and Young Adult Patients.Journal of adolescent and young adult oncology · 2022Article
- Self-reported cognitive outcomes among adolescent and young adult patients with noncentral nervous system cancers.Psycho-oncology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCancer-related cognitive impairment (CRCI) among adolescent and young adult (AYA) cancer patients with noncentral nervous system (CNS) cancers has not been well studied. In this study, we aimed to describe CRCI-associated trends and characteristics among AYA cancer patients.
methodsIn a longitudinal cohort of AYA cancer patients without CNS disease, CRCI was evaluated over 1 year using the Functional Assessment of Cancer Therapy-Cognitive Function Instrument, a self-reported cognitive outcome measure. CRCI prevalence was quantified using the previously established minimal clinically important difference. CRCI-associated longitudinal trends and factors were evaluated with mixed-effects model analysis.
resultsNinety-one patients (mean age = 28.4 ± 6.7 years) were included. Approximately one-third (34.1%) experienced CRCI at least once during the study follow-up. Female gender (P = .02), Indian ethnicity (P < .01), current smokers (P < .01), anxiety/depressive symptoms (P < .01) and fatigue (P < .01) were found to be associated with poorer cognitive function among AYAs.
conclusionsAlthough AYA cancer patients were relatively young and without CNS disease involvement, a significant proportion of them experienced clinically important decline in cognitive function. With improved understanding of this subject, effective strategies can be formulated to promote awareness of CRCI and mitigate its negative effects among AYA cancer patients.
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