ArticleAngewandte Chemie (International ed. in English)2020
Toward Artificial Mussel-Glue Proteins: Differentiating Sequence Modules for Adhesion and Switchable Cohesion.
Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 52 citations in OpenAlex.
- Transformative Masked Ortho-Quinone Chemistry: From Direct Guaiacol Activation to Lignin-Based Adhesives.Angewandte Chemie (International ed. in English) · 2026Article
- Towards synthetic catechol rich protein analogues through tyrosinase catalyzed activation of a tyrosine dipeptide in continuous mode.Catalysis science & technology · 2025Article
- Strength from Within: Reversible Reinforcement of Paper through In-Sheet Formation of Thiol-Catechol Polymers.ACS applied materials & interfaces · 2025Article
- Unlocking the Essence of Lignin: High-Performance Adhesives That Bond via Thiol-Catechol Connectivities and Debond on Electrochemical Command.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Recent advancements in smart responsive tissue adhesives for medical applications.Frontiers in medicine · 2025Review
- Enhancing Adhesion Properties of Commodity Polymers through Thiol-Catechol Connectivities: A Case Study on Polymerizing Polystyrene-Telechelics via Thiol-Quinone Michael-Polyaddition.ACS macro letters · 2024Article
- Tyrosinases: a family of copper-containing metalloenzymes.Chemtexts · 2024Article
- Femtosecond Laser Direct Writing of Gecko-Inspired Switchable Adhesion Interfaces on a Flexible Substrate.Micromachines · 2023Article
- Switchable Adhesion: On-Demand Bonding and Debonding.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Bio-based and bio-inspired adhesives from animals and plants for biomedical applications.Materials today. Bio · 2022Review
- Accessing the Next Generation of Synthetic Mussel-Glue Polymers via Mussel-Inspired Polymerization.Angewandte Chemie (International ed. in English) · 2021Article
- Toward Artificial Mussel-Glue Proteins: Differentiating Sequence Modules for Adhesion and Switchable Cohesion.Angewandte Chemie (International ed. in English) · 2020Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Artificial mussel-glue proteins with pH-triggered cohesion control were synthesized by extending the tyrosinase activated polymerization of peptides to sequences with specific modules for cohesion control. The high propensity of these sequence sections to adopt β-sheets is suppressed by switch defects. This allows enzymatic activation and polymerization to proceed undisturbed. The β-sheet formation is regained after polymerization by changing the pH from 5.5 to 6.8, thereby triggering O→N acyl transfer rearrangements that activate the cohesion mechanism. The resulting artificial mussel glue proteins exhibit rapid adsorption on alumina surfaces. The coatings resist harsh hypersaline conditions, and reach remarkable adhesive energies of 2.64 mJ m
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