Evidence map›Paper›PMID 32596877›Full record

Trial reportTransfusion2020

Machine learning-based prediction of transfusion.

Andreas Mitterecker, Axel Hofmann, Kevin M Trentino, Adam Lloyd, Michael F Leahy, Karin Schwarzbauer, Thomas Tschoellitsch, Carl Böck, Sepp Hochreiter, Jens Meier

Open access · hybridAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Transfusion, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Analysis of the Efficacy of Red Blood Cell Transfusion in Very Low Birth Weight Infants and Construction of a Prediction Model.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2026
    Article
  3. AI and Blood Banking: Predicting Transfusion Demand - A Systematic Review of Forecasting Approaches.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Andreas MittereckerInstitute for Machine Learning, Johannes Kepler University, Linz, Austria.ORCID 0000-0003-0888-8959
Axel HofmannDepartment of Anesthesiology and Critical Care Medicine, University and University Hospital, Zürich, Switzerland.
Kevin M TrentinoData and Digital Innovation, East Metropolitan Health Service, Perth, Australia.
Adam LloydData and Digital Innovation, East Metropolitan Health Service, Perth, Australia.
Michael F LeahyDepartment of Haematology, PathWest Laboratory Medicine, Royal Perth Hospital, Perth, Australia.
Karin SchwarzbauerInstitute for Machine Learning, Johannes Kepler University, Linz, Austria.
Thomas TschoellitschDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital GmbH and Johannes Kepler University, Linz, Austria.
Carl BöckDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital GmbH and Johannes Kepler University, Linz, Austria.
Sepp HochreiterInstitute for Machine Learning, Johannes Kepler University, Linz, Austria.
Jens MeierDepartment of Anesthesiology and Critical Care Medicine, Kepler University Hospital GmbH and Johannes Kepler University, Linz, Austria.
Johannes Kepler University of Linz · ATNorth Metropolitan Health Service · AURoyal Perth Hospital · AUUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ability to predict transfusions arising during hospital admission might enable economized blood supply management and might furthermore increase patient safety by ensuring a sufficient stock of red blood cells (RBCs) for a specific patient. We therefore investigated the precision of four different machine learning-based prediction algorithms to predict transfusion, massive transfusion, and the number of transfusions in patients admitted to a hospital. STUDY DESIGN AND

methodsThis was a retrospective, observational study in three adult tertiary care hospitals in Western Australia between January 2008 and June 2017. Primary outcome measures for the classification tasks were the area under the curve for the receiver operating characteristics curve, the F

resultsUsing our four predictive models, transfusion of at least 1 unit of RBCs could be predicted rather accurately (sensitivity for NN, LR, RF, and GB: 0.898, 0.894, 0.584, and 0.872, respectively; specificity: 0.958, 0.966, 0.964, 0.965). Using the four methods for prediction of massive transfusion was less successful (sensitivity for NN, LR, RF, and GB: 0.780, 0.721, 0.002, and 0.797, respectively; specificity: 0.994, 0.995, 0.993, 0.995). As a consequence, prediction of the total number of packed RBCs transfused was also rather inaccurate.

conclusionThis study demonstrates that the necessity for intrahospital transfusion can be forecasted reliably, however the amount of RBC units transfused during a hospital stay is more difficult to predict.

Indexed as

Decision Making, Computer-AssistedHospitalizationMachine LearningAdultBlood TransfusionFemaleHumansMalePredictive Value of TestsRetrospective StudiesWestern Australia

Identifiers

PMID32596877
PMCPMC7540018
OpenAlexW3037935766

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.