ReviewAdvances in experimental medicine and biology2021
The Role of Gram-Negative Bacteria in Urinary Tract Infections: Current Concepts and Therapeutic Options.
Review in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Pooled it
- Efficacy and safety of Chinese patent medicine for urinary tract infections: a systematic review and network meta-analysis.Frontiers in medicine · 2025Pooled it
- Insights into antimicrobial resistance: dissemination and molecular epidemiology of carbapenemase and AmpC genes in uropathogenic Escherichia coli.BMC microbiology · 2026Article
- Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026Review
- Uropathogens and prognosis among patients with hospital-diagnosed acute pyelonephritis: insights from a 19-year population-based cohort study.Infection · 2026Article
- Prevalence, antibiotic susceptibility and associated risk factors for extended spectrum beta-lactamase-producing Enterobacteriaceae among patients suspected with urinary tract infection at Nigist Eleni Mohammed Memorial Hospital, Ethiopia.BMC infectious diseases · 2026Article
- Distribution and Drug-Resistance Analysis of Uropathogens in Urinary Tract Infections.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026Article
- Article
- Comparative genomic and phenotypic analysis of Escherichia coli ST1193 and ST131 from urinary and bloodstream infections: insights into resistance, virulence, and divergent strategies.BMC infectious diseases · 2025Article
- Regional Burden of Urinary Tract Infection, Its Aetiologies, and Antibiotic Resistance Patterns, 2020-2023: A Retrospective Study.Health science reports · 2025Article
- Distribution of antimicrobial resistance genes and virulence genes in different genotypes of Acinetobacter baumannii.BMC infectious diseases · 2025Article
- Carbapenem-ResistantMicroorganisms · 2025Review
- Exploring Antibiotic Resistance Patterns inJournal of clinical medicine · 2025Article
- Bioactive Compounds as Alternative Approaches for Preventing Urinary Tract Infections in the Era of Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- Uropathogen profiles and their antimicrobial resistance patterns in patients: a three-year retrospective study in Sichuan region.Frontiers in public health · 2025Article
- Trends inAntibiotics (Basel, Switzerland) · 2024Article
- Distribution of chaperone-usher fimbriae and curli fimbriae among uropathogenic Escherichia coli.BMC microbiology · 2024Article
- Rapid Determination of Positive-Negative Bacterial Infection Based on Micro-Hyperspectral Technology.Sensors (Basel, Switzerland) · 2024Article
- Antibacterial and antioxidant activities of plants consumed by western lowland gorilla (Gorilla gorilla gorilla) in Gabon.PloS one · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urinary tract infections (UTIs) are some of the most common infections in human medicine worldwide, recognized as an important public health concern to healthcare systems around the globe. In addition, urine specimens are one of the most frequently submitted samples for culture to the clinical microbiology laboratory, exceeding the number of most of the other sample types. The epidemiology, species-distribution and susceptibility-patterns of uropathogens vary greatly in a geographical and time-dependent manner and it also strongly correlated with the reported patient population studied. Nevertheless, many studies highlight the fact that the etiological agents in UTIs have changed considerably, both in nosocomial and community settings, with a shift towards "less common" microorganisms having more pronounced roles. There is increasing demand for further research to advance diagnostics and treatment options, and to improve care of the patients. The aim of this review paper was to summarize current developments in the global burden of UTI, the diagnostic aspects of these infectious pathologies, the possible etiological agents and their virulence determinants (with a special focus on the members of the Enterobacterales order), current guidelines and quality indicators in the therapy of UTIs and the emergence of multidrug resistance in urinary pathogens.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.