ArticleOsteoarthritis and cartilage open2020
The association between comorbidity and physical activity levels in people with osteoarthritis: Secondary analysis from two randomised controlled trials.
Article in Osteoarthritis and cartilage open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Physical Activity Knowledge in People With Knee Osteoarthritis Before and After Participation in an Education and Exercise Therapy Programme.Musculoskeletal care · 2026Observational
- Unsupervised machine learning models reveal two distinct post-operative physical activity profiles among joint arthroplasty patients: a United Kingdom biobank cohort study.Arthroplasty (London, England) · 2025Article
- Article
- Does osteoarthritis physiotherapy research in South Korea align with the National Institute for Health and Care Excellence guidelines: a systematic review of English and Korean literature.BMC rheumatology · 2025Article
- Association Between Depressive Symptoms and Self-Reported Physical Activity in Persons With Knee Osteoarthritis.The Journal of rheumatology · 2025Article
- A Higher Charlson Comorbidity Index Is a Risk Factor for Hip Fracture in Older Adults During Low-Temperature Periods: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2024Article
- Impact of motivational feedback on levels of physical activity and quality of life by activity monitoring following knee arthroplasty surgery-protocol for a randomized controlled trial nested in a prospective cohort (Knee-Activity).BMC musculoskeletal disorders · 2024Article
- The OARSI Joint Effort Initiative: Priorities for osteoarthritis management program implementation and research 2024-2028.Osteoarthritis and cartilage open · 2023Article
- The relationship between experience of knee pain and physical activity participation: A scoping review of quantitative studies.International journal of nursing sciences · 2023Article
- Psychological comorbidities in osteoarthritis in Germany.Scientific reports · 2023Article
- A Nomogram for Predicting Non-Response to Surgery One Year after Elective Total Hip Replacement.Journal of clinical medicine · 2022Article
- Factors Affecting Physical Activity of People with Knee Osteoarthritis in Southern Taiwan: A Multiple Logistic Regression Analysis.International journal of clinical practice · 2022Article
- Barriers to and Facilitators of Physical Activity among Korean Female Adults with Knee Osteoarthritis and Comorbidity: A Qualitative Study.Healthcare (Basel, Switzerland) · 2020Article
- Integrated Virtual Exercise for Older Adults in Remote Patient Monitoring Program: A Feasibility Study.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine whether comorbidity presence, frequency or type is associated with Physical Activity (PA) levels in people with Osteoarthritis (OA).
designSecondary data analysis of adults aged ≥45, with OA related pain recruited to the BEEP trial (knee pain, n = 514) (ISRCTN93634563) and the MOSAICS trial (peripheral joint pain, n = 525) (ISRCTN06984617). Comorbidities considered were respiratory, cardiovascular diseases (CVD), depression, type 2 diabetes and obesity. Self-report PA was measured using the Physical Activity Scale for the Elderly (PASE). Linear regression models were used to estimate the mean change (β) in PA with comorbidity presence, frequency and type adjusting for potential confounding covariates.
resultsIn the BEEP trial comorbidity presence was associated with a decrease in PASE score (β = -32.25 [95% confidence interval (95% CI) -48.57, -15.93]). Each additional comorbidity was associated with an incrementally lower PASE score, one comorbidity (β = -24.42 [-42.45, -6.38]), two comorbidities β = -34.76 [-56.05, -13.48]), and three or more comorbidities β = -73.71 [-106.84, -40.58]) compared to those with no comorbidity. This pattern was similar in MOSAICS, but with a plateau in association from two comorbidities onward. In BEEP and MOSAICS, respiratory (β = -40.60 [-60.50, -20.35]; β = -11.82 [-34.95, 11.31]) and CVD (β = -27.15 [-53.25, -1.05]; β = -30.84 [-51.89, -9.80]) comorbidities were associated with the largest reduction in PASE scores respectively.
conclusionComorbidity presence and frequency is associated with lower PA levels and respiratory and CVD comorbidities have the greatest impact. Future exploratory work needs to be done to understand how and why comorbidity is associated with PA levels in people with OA.
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