Evidence map›Paper›PMID 32596690›Full record

ArticleBMC chemistry2020

Bioactive fluorenes. Part III: 2,7-dichloro-9

Essam M Hussein, Reem I Alsantali, Moataz Morad, Rami J Obaid, Hatem M Altass, Ali Sayqal, Mohamed A S Abourehab, Amal A Elkhawaga, Ahmed S M Aboraia, Saleh A Ahmed

Open access · goldAbstract read
In one paragraph

Article in BMC chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. 4-Thiazolidinone-Bearing Hybrid Molecules in Anticancer Drug Design.International journal of molecular sciences · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Essam M HusseinDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, 21955 Saudi Arabia.
Reem I AlsantaliDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, 21955 Saudi Arabia.
Moataz MoradDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, 21955 Saudi Arabia.
Rami J ObaidDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, 21955 Saudi Arabia.
Hatem M AltassDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, 21955 Saudi Arabia.
Ali SayqalDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, 21955 Saudi Arabia.
Mohamed A S AbourehabDepartment of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Amal A ElkhawagaDepartment of Medical Microbiology & Immunology, Faculty of Medicine Assiut University, Assiut, 71516 Egypt.
Ahmed S M AboraiaDepartment of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut, 71516 Egypt.
Saleh A AhmedDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, 21955 Saudi Arabia.ORCID 0000-0002-2364-0380
Umm al-Qura University · SAAssiut University · EGTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThiazoles, thiazolidinones and azetidinones are highly ranked amongst natural and synthetic heterocyclic derivatives due to their great pharmaceutical potential.

resultsNew thiazolidinone and azetidinone class of bioactive agents based on 4-(2,7-dichloro-9

conclusionSome of the synthesized compounds showed remarkable activity against A-549 and MDA-MB-231 when compared to Taxol, which was used as a reference drug. 2,7-dichloro-9

Indexed as

Anti-cancerAntimicrobialAzetidinonesFACSFluoreneMolecular dockingPharmacophoresThiazolidinones

Identifiers

PMID32596690
PMCPMC7315563
OpenAlexW3037983920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.