ArticleACS omega2020
Shaking-Induced Aggregation and Flotation in Immunoglobulin Dispersions: Differences between Water and Water-Ethanol Mixtures.
Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 73 citations in OpenAlex.
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- Resonant Oscillations of Ion-Stabilized Nanobubbles in Water as a Possible Source of Electromagnetic Radiation in the Gigahertz Range.International journal of molecular sciences · 2025Article
- Diversity of Effects of Mechanical Influences on Living Systems and Aqueous Solutions.International journal of molecular sciences · 2025Review
- Non-Contact Interaction Between Phorbol Myristate Acetate and Aqueous Alcohol Solutions Under Combined Magnetic Fields.Molecules (Basel, Switzerland) · 2024Article
- Size control of precipitated particles of amino acids using a bubble column evaporator.Heliyon · 2023Article
- Modeling of protein hydration dynamics is supported by THz spectroscopy of highly diluted solutions.Frontiers in chemistry · 2023Article
- Deep learning applied to analyze patterns from evaporated droplets of Viscum album extracts.Scientific reports · 2022Article
- Diclofenac Ion Hydration: Experimental and Theoretical Search for Anion Pairs.Molecules (Basel, Switzerland) · 2022Article
- Nafion Swelling in Salt Solutions in a Finite Sized Cell: Curious Phenomena Dependent on Sample Preparation Protocol.Polymers · 2022Article
- Pulmonary surfactant and COVID-19: A new synthesis.QRB discovery · 2022Article
- Optical Properties of Crystalline Lactose Fluidized with Dilutions of Various Substances in the Terahertz Frequency Range.Pharmaceutics · 2021Article
- Antibodies Processed Using High Dilution Technology Distantly Change Structural Properties of IFNγ Aqueous Solution.Pharmaceutics · 2021Article
- New insights into the microscopic interactions associated with the physical mechanism of action of highly diluted biologics.Scientific reports · 2021Article
- Structure and refractive index of fibrin protofibril aggregates according to laser phase microscopy accompanied by DLS and AFM.Biomedical optics express · 2021Article
- Formation of Water-Free Cavity in the Process of Nafion Swelling in a Cell of Limited Volume; Effect of Polymer Fibers Unwinding.Polymers · 2020Article
- Effect of Mechanical Shaking on the Physicochemical Properties of Aqueous Solutions.International journal of molecular sciences · 2020Article
- Effect of Frequency of Prospekta Administration: Anxiolytic Effect in Wistar Rats.Dose-response : a publication of International Hormesis SocietyArticle
- Highly Diluted Antibodies to eNOS Restore Endothelium Function in Aortic Rings From Hypertensive Rats.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Structural characterization by three complementary methods of laser diagnostics (dynamic light scattering, laser phase microscopy, and laser polarimetric scatterometry) has established that shaking of immunoglobulin G (IgG) dispersions in water and ethanol-water mixtures (36.7 vol %) results in two effects. First, it intensifies the aggregation of IgG macromolecules. Second, it generates bubbles with a size range that is different in each solvent. The aggregation is enhanced in ethanol-water mixtures because of IgG denaturation. IgG aggregates have a size of ∼300 nm in water and ∼900 nm in ethanol-water mixtures. The flotation of IgG is much more efficient in water. This can be explained by a better adsorption of IgG particles (molecules and aggregates) on bubbles in water as compared to ethanol-water mixtures. Bulk nanobubbles and their association with IgG aggregates were visualized by laser phase microscopy in water but were not detected in ethanol-water mixtures. Therefore, the nanobubble flotation mechanism for IgG aggregates acting in water is not feasible for ethanol-water mixtures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.