Evidence map›Paper›PMID 32596554›Full record

ArticleBioactive materials2020

Calcium-mineralized polypeptide nanoparticle for intracellular drug delivery in osteosarcoma chemotherapy.

Ke Li, Di Li, Li Zhao, Yonghe Chang, Yi Zhang, Yan Cui, Zhiyu Zhang

Abstract read
In one paragraph

Article in Bioactive materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  12. Recent Developments in CaCOPharmaceutics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ke LiDepartment of Orthopedics, The Fourth Affiliated Hospital of China Medical University, 4 Chongshandong Road, Shenyang 110032, People's Republic of China.
Di LiKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, People's Republic of China.
Li ZhaoLaboratory of Building Energy-Saving Technology Engineering, College of Material Science and Engineering, Jilin Jianzhu University, 5088 Xincheng Street, Changchun 130118, People's Republic of China.
Yonghe ChangDepartment of Orthopedics, The Fourth Affiliated Hospital of China Medical University, 4 Chongshandong Road, Shenyang 110032, People's Republic of China.
Yi ZhangDepartment of Orthopedics, The Fourth Affiliated Hospital of China Medical University, 4 Chongshandong Road, Shenyang 110032, People's Republic of China.
Yan CuiDepartment of Orthopedics, The Fourth Affiliated Hospital of China Medical University, 4 Chongshandong Road, Shenyang 110032, People's Republic of China.
Zhiyu ZhangDepartment of Orthopedics, The Fourth Affiliated Hospital of China Medical University, 4 Chongshandong Road, Shenyang 110032, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acidic microenvironments of tumor tissue and cells provide an opportunity for the development of pH-responsive drug delivery systems in cancer therapy. In this work, we designed a calcium carbonate (CaCO

Indexed as

Calcium mineralizationControlled drug releaseOsteosarcoma chemotherapypH-responsivenessPolypeptide

Identifiers

PMID32596554
PMCPMC7298657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.