Evidence map›Paper›PMID 32596507›Full record

ArticleNPJ precision oncology2020

Liquid biopsy mutation panel for non-small cell lung cancer: analytical validation and clinical concordance.

Lee S Schwartzberg, Hidehito Horinouchi, David Chan, Sara Chernilo, Michaela L Tsai, Dolores Isla, Carles Escriu, John P Bennett, Kim Clark-Langone, Christer Svedman and 2 more

Open access · goldAbstract read
In one paragraph

Article in NPJ precision oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Liquid Biopsy in Solid Tumours: An Overview.Cytopathology : official journal of the British Society for Clinical Cytology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Concordance Between TissueJTO clinical and research reports · 2022
    Article
  16. Multi-Modal Microfluidics (MMicromachines · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 6 countries.

Lee S SchwartzbergWest Cancer Center & Research Institute, 7945 Wolf River Boulevard, Germantown, TN 38138 USA.
Hidehito HorinouchiNational Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045 Japan.ORCID 0000-0001-9090-801X
David ChanCancer Care Associates TMPN (now Hunt Cancer Center), 3285 Skypark Dr, Torrance, CA 90505 USA.
Sara CherniloInstituto Nacional del Tórax, José Manuel Infante 717, segundo piso, Providencia, 7500691 Santiago, Chile.
Michaela L TsaiVirginia Piper Cancer Institute, Minnesota Oncology, 800 E 28th St., Suite 602, Minneapolis, MN 55407 USA.
Dolores IslaUniversity Hospital Lozano Blesa, Avda. S. Juan Bosco no 15, 50009 Zaragoza, Spain.
Carles EscriuThe Clatterbridge Cancer Centre, Clatterbridge Road, Bebington, Wirral, CH63 4JK UK.
John P BennettGenomic Health, Inc. (now Exact Sciences Corp.), 301 Penobscot Dr, Redwood City, CA 94063 USA.ORCID 0000-0001-5184-7912
Kim Clark-LangoneGenomic Health, Inc. (now Exact Sciences Corp.), 301 Penobscot Dr, Redwood City, CA 94063 USA.
Christer SvedmanGenomic Health, Inc. (now Exact Sciences Corp.), 301 Penobscot Dr, Redwood City, CA 94063 USA.
Pascale TomasiniAssistance Publique Hôpitaux de Marseille, and Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068, CNRS UMR7258, Aix-Marseille Université, UM105 Marseille, France.
Oncotype SEQ® Study Investigators and Program Team
Exact Sciences (United States) · USGabrail Cancer Center · USNavicent Health · USSt. Francis Medical Center · USCentre National de la Recherche Scientifique · FRClatterbridge Cancer Centre NHS Foundation Trust · GBHospital Clínico Universitario Lozano Blesa · ESInstituto Nacional del Tórax · CLMinnesota Oncology · USSkin Cancer Foundation · USWest Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular testing for genomic variants is recommended in advanced non-small cell lung cancer (NSCLC). Standard tissue biopsy is sometimes infeasible, procedurally risky, or insufficient in tumor tissue quantity. We present the analytical validation and concordance study of

Indexed as

Cancer genomics

Identifiers

PMID32596507
PMCPMC7314769
OpenAlexW3038083597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.