Evidence map›Paper›PMID 32596459›Full record

ArticleScience advances2020

Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression.

Jian Han, Omer An, HuiQi Hong, Tim Hon Man Chan, Yangyang Song, Haoqing Shen, Sze Jing Tang, Jaymie Siqi Lin, Vanessa Hui En Ng, Daryl Jin Tai Tay and 5 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
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  10. Modulation of mProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Biallelic variants inmedRxiv : the preprint server for health sciences · 2024
    Article
  12. Article
  13. The role of ADAR1 through and beyond its editing activity in cancer.Cell communication and signaling : CCS · 2024
    Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Jian HanCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0003-2260-9784
Omer AnCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0002-5762-6253
HuiQi HongCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Tim Hon Man ChanCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Yangyang SongCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0003-1666-2706
Haoqing ShenCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0003-1721-1536
Sze Jing TangCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0002-4258-6367
Jaymie Siqi LinCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Vanessa Hui En NgCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0001-8668-1801
Daryl Jin Tai TayCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0002-4082-9281
Fernando Bellido MoliasCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0001-5003-7141
Priyankaa PitcheshwarCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Hui Qing TanDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117549, Singapore.ORCID 0000-0003-4927-9316
Henry YangCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.
Leilei ChenCancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0002-1987-3878
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA editing introduces nucleotide changes in RNA sequences. Recent studies have reported that aberrant A-to-I RNA editing profiles are implicated in cancers. Albeit changes in expression and activity of

Indexed as

AdenosineApoptosis Regulatory ProteinsNeoplasmsRNA-Binding ProteinsAdenosine DeaminaseHumansInosineRNAAdenosineAdenosine DeaminaseApoptosis Regulatory ProteinsDAP3 protein, humanInosineRNARNA-Binding Proteins

Identifiers

PMID32596459
PMCPMC7299630
OpenAlexW3035991984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.