Evidence map›Paper›PMID 32596401›Full record

ArticleBioMed research international2020

GGTA1/iGb3S Double Knockout Mice: Immunological Properties and Immunogenicity Response to Xenogeneic Bone Matrix.

Anliang Shao, You Ling, Liang Chen, Lina Wei, Changfa Fan, Dan Lei, Liming Xu, Chengbin Wang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anliang ShaoMedical School of Chinese PLA & Medical Laboratory Center, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
You LingNational Engineering Laboratory for Regenerative Medical Implant Devices, Guanhao Biotech, Co., Ltd., Guangzhou 510530, China.
Liang ChenInstitute for Medical Device Control, National Institutes for Food and Drug Control, Beijing 102629, China.
Lina WeiInstitute for Medical Device Control, National Institutes for Food and Drug Control, Beijing 102629, China.
Changfa FanInstitute for Laboratory Animal Resources, National Institutes for Food and Drug Control, Beijing 102629, China.
Dan LeiNational Engineering Laboratory for Regenerative Medical Implant Devices, Guanhao Biotech, Co., Ltd., Guangzhou 510530, China.
Liming XuInstitute for Medical Device Control, National Institutes for Food and Drug Control, Beijing 102629, China.ORCID https://orcid.org/0000-0002-3577-0959
Chengbin WangMedical School of Chinese PLA & Medical Laboratory Center, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.ORCID https://orcid.org/0000-0002-6535-5967
National Institutes for Food and Drug Control · CNChinese PLA General Hospital · CNGuangzhou Regenerative Medicine and Health Guangdong Laboratory · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnimal tissues and tissue-derived biomaterials are widely used in the field of xenotransplantation and regenerative medicine. A potential immunogenic risk that affects the safety and effectiveness of xenografts is the presence of remnant

methods

results

conclusionG/i DKO mice are sensitive to Gal antigen-positive xenogeneic grafts and can be effectively utilized for evaluating the

Indexed as

Bone MatrixTransplantation, Heterologousalpha-GalactosidaseAnimalsBone SubstitutesCattleErythrocytesGalactosyltransferasesHeterograftsMiceMice, KnockoutRabbitsalpha-GalactosidaseBone SubstitutesGalactosyltransferases

Identifiers

PMID32596401
PMCPMC7292995
OpenAlexW3033868468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.