SynthesisBioMed research international2020
The Induced Membrane Technique for the Management of Segmental Tibial Defect or Nonunion: A Systematic Review and Meta-Analysis.
Synthesis in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Induced Membrane Technique for the Management of Segmental Femoral Defects: A Systematic Review and Meta-Analysis of Individual Participant Data.Orthopaedic surgery · 2023Pooled it
- The road to the Pearl-String Technique: lessons learned from early IMT modifications using RIA autograft and cancellous allograft granules.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Clinical Characteristics of Patients with Long-Bone Fracture Nonunion and Delayed Union and Factors Associated with Infection: A Retrospective Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique.BMC surgery · 2025Article
- Custom-Made 3D-Printed Titanium Implants for Managing Segmental Distal Tibial Bone Defects: A Systematic Literature Review.Journal of clinical medicine · 2025Review
- Clinical Observations of the Effectiveness of the Masquelet Induced Membrane Technique in the Treatment of Critical Long-Bone Defects of the Lower and Upper Extremities.Medicina (Kaunas, Lithuania) · 2024Article
- [Modified Masquelet technique : Technique of the induced membrane in the course of time].Unfallchirurgie (Heidelberg, Germany) · 2024Article
- Does the extent of bone defects affect the time to reach full weight-bearing after treatment with the Masquelet technique?Biomaterials and biosystems · 2024Article
- Management of Infected Gap Non-union of Distal Femur with Induced Membrane Technique using Limb Reconstruction System Followed by Augmentation Plating and Bone Grafting: A Case Report.Journal of orthopaedic case reports · 2024Article
- Management of infected bone defects of the femoral shaft by Masquelet technique: sequential internal fixation and nail with plate augmentation.BMC musculoskeletal disorders · 2024Article
- Review
- Semi-focal bone transport versus traditional bone transport technique for the management of large tibial bone defects after trauma.Scientific reports · 2024Article
- [Diagnostic and therapeutic work-up of infected tibial nonunion].Unfallchirurgie (Heidelberg, Germany) · 2024Review
- Application study of multidisciplinary collaboration (MDT) integrated management model in perioperative management of patients with infectious nonunion.Frontiers in surgery · 2024Article
- FixThePig: a custom 3D-printed femoral intramedullary nailing for preclinical research applications.Frontiers in bioengineering and biotechnology · 2024Article
- Comparative bone healing with induced membrane technique (IMT) versus empty defects in septic and aseptic conditions in a novel rabbit humerus model.BMC musculoskeletal disorders · 2023Article
- Matched-Pair Analysis: Large-Sized Defects in Surgery of Lower Limb Nonunions.Journal of clinical medicine · 2023Article
- Management of bone loss in acute severe open tibial fractures: a retrospective study of twenty nine cases-a treatment strategy with bone length preservation.International orthopaedics · 2023Article
- Masquelet technique in military practice: specificities and future directions for combat-related bone defect reconstruction.Military Medical Research · 2022Review
- Induced membrane technique for acute bone loss and nonunion management of the tibia.OTA international : the open access journal of orthopaedic trauma · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo identify the predicting factors for union and infection after applying the induced membrane technique (IMT) for segmental tibial defects.
methodsA systematic review was carried out following the PRISMA guidelines. All databases were searched for articles published between January 2000 and February 2018 using the keywords "Masquelet technique" and "induced membrane technique." Studies in English reporting more than 5 cases with accessible individual patient data were included. A meta-analysis was performed. Odds ratios (OR) with 95% confidence intervals were calculated.
resultsAfter reviewing, 11/243 studies (115 patients) were finally selected. The mean age of the patients was 43.6 years (range: 18-84 years), and the mean length of the tibial defect was 5.5 cm (range: 0-20 cm). The multivariate logistic regression analysis revealed that the risk factors of postoperative infection after IMT were infected nonunion (
conclusionsIMT is a reliable and reproducible treatment for segmental tibial defects. However, initial infected nonunion and defect length greater than 7 cm are risk factors for post-IMT infection, and post-IMT infection was statistically related to nonunion.
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