ArticleBioMed research international2020
Reference Values of D-Dimers and Fibrinogen in the Course of Physiological Pregnancy: the Potential Impact of Selected Risk Factors-A Pilot Study.
Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Fibrinogen Deficiency and Dysfunction in Postpartum Hemorrhage: Evidence, Thresholds, and Management Across Resource Settings.Journal of clinical medicine · 2026Review
- Evaluation of Systemic Inflammatory Indices in Pregnant Women With Deep Vein Thrombosis.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Article
- A Narrative Review on Abnormalities in the Hemostatic System in Diabetes Mellitus: Pathophysiology, Clinical Implications, and Therapeutics.Life (Basel, Switzerland) · 2026Review
- Article
- Obesity Is a Thrombotic Risk Factor in Pregnant Women.Journal of clinical medicine · 2025Article
- Soluble Fibrin Monomer Complex and D-Dimer Concentrations Between Patients at Low and High Risk of Venous Thromboembolism Before Delivery According to RCOG Score Assessment: An Observational Study Among 100 Third-Trimester Vietnamese Pregnancies.Journal of clinical medicine · 2025Article
- Improving Clinical Prediction of Pulmonary Embolism in Pregnancy and Postpartum by Modifying Wells Score with a Population Specific Risk Factor:Sultan Qaboos University medical journal · 2025Article
- The clinical significance of D-dimer concentrations predicting the risk of venous thromboembolism in patients with hyperemesis gravidarum.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Proteomic analysis of plasma total exosomes and placenta-derived exosomes in patients with gestational diabetes mellitus in the first and second trimesters.BMC pregnancy and childbirth · 2024Article
- Article
- Placental Origins of Preeclampsia: Insights from Multi-Omic Studies.International journal of molecular sciences · 2024Review
- Associations of serum D-dimer and glycosylated hemoglobin levels with third-trimester fetal growth restriction in gestational diabetes mellitus.World journal of diabetes · 2024Article
- Impact of Thrombophilic Polymorphisms in Antenatal Women on Perinatal Health: A Single-Center Prospective Study.Journal of personalized medicine · 2024Article
- Maternal and Newborn Characteristics-A Comparison between Healthy and Thrombophilic Pregnancy.Life (Basel, Switzerland) · 2023Article
- Comparison of Maternal and Neonatal Outcomes between SARS-CoV-2 Variants: A Retrospective, Monocentric Study.Journal of clinical medicine · 2023Article
- Approach to Thrombophilia in Pregnancy-A Narrative Review.Medicina (Kaunas, Lithuania) · 2022Review
- Reference intervals for coagulation parameters in non-pregnant and pregnant women.Scientific reports · 2022Article
- SARS-CoV-2 and the Immune Response in Pregnancy with Delta Variant Considerations.Infectious disease reports · 2021Review
- Investigation of the Molecular Mechanism of Coagulopathy in Severe and Critical Patients With COVID-19.Frontiers in immunology · 2021Article
- Differences in Clinical and Laboratory Features of Pregnant and Non-Pregnant Female with Hospitalized COVID-19.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy predisposes to thrombotic hemostasis, reflected in the laboratory as, e.g., increased levels of D-Dimers and fibrinogen, but in physiological pregnancy, the risk of venous thrombosis does not increase. Risk may increase if gestational diabetes mellitus (GDM) or nicotinism coexists. Study aims were to determine reference values for D-Dimers and fibrinogen concentrations in each trimester of pregnancy, corrected for GDM and nicotinism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.