Evidence map›Paper›PMID 32595966›Full record

ReviewJournal of nutritional science2020

The role of oligosaccharides and polysaccharides of xylan and mannan in gut health of monogastric animals.

Utsav P Tiwari, Stephen A Fleming, Muhammed S Abdul Rasheed, R Jha, Ryan N Dilger

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nutritional science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 63 citations in OpenAlex.

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  12. Review
  13. DietaryAquaculture nutrition · 2024
    Article
  14. Article
  15. Article
  16. Applications and prospects of functional oligosaccharides in pig nutrition: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Utsav P TiwariDepartment of Animal Sciences, University of Illinois, Urbana, IL, USA.
Stephen A FlemingDepartment of Animal Sciences, University of Illinois, Urbana, IL, USA.
Muhammed S Abdul RasheedDepartment of Animal Sciences, University of Illinois, Urbana, IL, USA.
R JhaDepartment of Human Nutrition, Food and Animal Sciences, University of Hawaii at Manoa, Honolulu, HI, USA.ORCID 0000-0002-2891-8353
Ryan N DilgerDepartment of Animal Sciences, University of Illinois, Urbana, IL, USA.ORCID 0000-0003-2538-2845
University of Illinois Urbana-Champaign · USUniversity of Hawaiʻi at Mānoa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apart from its role as a digestive and absorptive organ, the gastrointestinal (GI) tract is a vital immune organ that encompasses roughly 70 % of the total immune cells of the body. As such, the physical, chemical and nutrient composition of the diet influences overall GI function, effectively as an immune organ. With the improvement in feed technology, agro-industrial co-products that are high in fibre have been widely used as a feed ingredient in the diets of pigs and poultry. Arabinoxylan (AX) and mannan are the most abundant hemicellulosic polysaccharides present in cereal grain and co-product ingredients used in the livestock industry. When monogastric animals consume diets containing high amounts of AX and mannans, stimulation of GI immune cells may occur. This involves the activation of several cellular and molecular pathways of the immune system and requires a considerable amount of energy and nutrients to be expended by the animal, which may ultimately influence overall health and growth performance of animals. Therefore, a better understanding of the role of AX and mannan in immune modulation will be helpful in modulating untoward GI immune responses, thereby minimising nutrient and energy expenditure toward this effort. This review will summarise pertinent research on the role of oligosaccharides and polysaccharides containing AX and mannans in immune modulation in order to preserve gut integrity.

Indexed as

DietAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsDietary FiberDigestionEdible GrainGastrointestinal TractMannansMolecular WeightOligosaccharidesPolysaccharidesSolubilityViscosityXylansarabinoxylanDietary FiberMannansOligosaccharidesPolysaccharidesXylansArabinoxylanA:X, arabinose:xyloseAX, arabinoxylanCLTD, carbohydrate recognition domainDC, dendritic cellsGGM, galactoglucomannanGH, glycosidic hydrolaseGI, gastrointestinalImmune modulationMannanMBL, mannose-binding lectinMOS, mannan oligosaccharideMR, mannose receptorOligosaccharidesPAMP, pathogen-associated molecular patternPolysaccharidesTLR, toll-like receptorXOS, xylo-oligosaccharide

Identifiers

PMID32595966
PMCPMC7303790
OpenAlexW3034473762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.