ReviewFrontiers in psychiatry2020
The Impact of Subsyndromal Bipolar Symptoms on Patient's Functionality and Quality of Life.
Review in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Subsyndromal Depressive Symptoms in Bipolar Disorder: Associations with Functioning, Internalized Stigma, Impulsivity, and Anxiety.Brain sciences · 2026Article
- Bipolar Disorder in Older Adults: A Comprehensive Overview of Pharmacotherapy Patterns and Clinical Considerations.Drugs & aging · 2026Review
- GBR 12909, a Selective Dopamine Transporter Inhibitor, Differentially Modulates Affective, Exploratory and Cognitive Domains in Zebrafish.The European journal of neuroscience · 2026Article
- Understanding the Current State of Play of Early Intervention for Bipolar Disorder: Qualitative Analysis of Consultations With International Stakeholders.Bipolar disorders · 2026Article
- Stabilizing Sleep-Wake Cycles and Social Functioning in Bipolar Disorders: Effect of Interpersonal and Social Rhythm Therapy.Journal of clinical medicine · 2026Article
- Performance of active and passive ambulatory assessment measures and mood monitoring in bipolar disorder: a systematic review.International journal of bipolar disorders · 2026Review
- Experiences of informal caregivers supporting individuals diagnosed with bipolar disorder: a systematic review and thematic synthesis.International journal of bipolar disorders · 2025Review
- Article
- Social functioning in bipolar disorder: investigating the role played by comorbid physical illnesses and cognition.Dementia & neuropsychologia · 2025Article
- Neuromodulation Strategies in Lifelong Bipolar Disorder: A Narrative Review.Behavioral sciences (Basel, Switzerland) · 2024Review
- Relationships between cognition, functioning, and quality of life of euthymic patients with bipolar disorder: Structural equation modeling with the FACE-BD cohort.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Outcomes of Bariatric Surgery in Patients with Schizophrenia.Nutrients · 2024Article
- Protocol for a systematic review and meta-analysis of coordinate-based network mapping of brain structure in bipolar disorder across the lifespan.BJPsych open · 2023Article
- Prioritizing Treatment Goals of People Diagnosed with Bipolar I Disorder in the US: Best-Worst Scaling Results.Patient preference and adherence · 2023Article
- Real-World Functioning in Psychiatric Outpatients: Predictive Factors.Journal of clinical medicine · 2022Article
- Associations of emotion recognition, loneliness, and social functioning in euthymic patients with bipolar disorder.The Kaohsiung journal of medical sciences · 2022Article
- Psychological and behavioral response on the COVID-19 pandemic in individuals with bipolar disorder: A multicenter study.Psychiatry research · 2022Article
- Cognitive Processes and Legal Capacity in Patients With Bipolar Disorder: A Brief Research Report.Frontiers in psychology · 2022Article
- Hamlet's augury: how to manage discontinuation of mood stabilizers in bipolar disorder.Therapeutic advances in psychopharmacology · 2021Review
- Living With Bipolar Disorder in the Time of Covid-19: Biorhythms During the Severe Lockdown in Cagliari, Italy, and the Moderate Lockdown in Tunis, Tunisia.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subsyndromal symptoms have rarely been in the focus of bipolar research. This may be, in part, due to the fact that there is neither a uniform definition nor do they constitute an indication of regulatory and commercial interest. Nevertheless, they do have a decisive impact on the long-term course of bipolar disorder (BD), and the degree of functionality and quality of life (QoL) is more likely determined by their presence or absence than by acute episodes. Summarizing the literature an estimated 20-50% of patients suffer inter-episodically or chronically from subsyndromal BD. The most prominent symptoms that interfere with functionality are subsyndromal depression, disturbances of sleep, and perceived cognitive impairment, whereas anxiety negatively impacts on QoL. In the absence of evidence-based pharmacological treatments for subsyndromal BD, clinical practice adopts guidelines designed for treatment-resistant full-blown episodes of BD, supplemented by cognitive-behavioral, family focused or social-rhythm-based psychotherapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.