Evidence map›Paper›PMID 32595358›Full record

ArticleTurkish journal of biology = Turk biyoloji dergisi2020

An insight into the epitope-based peptide vaccine design strategy and studies against COVID-19.

Murat TopuzoĞullari, Tayfun Acar, Pelin Pelİt Arayici, Burcu UÇar, Erennur UĞurel, Emrah Şefik Abamor, Tülin ArasoĞlu, Dilek Turgut-Balik, Serap Derman

Abstract read
In one paragraph

Article in Turkish journal of biology = Turk biyoloji dergisi, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A novel vaccine based on SARS-CoV-2 CD4Scientific reports · 2022
    Article
  8. Review
  9. Article
  10. Peptides for Vaccine Development.ACS applied bio materials · 2022
    Review
  11. Therapeutic peptides: current applications and future directions.Signal transduction and targeted therapy · 2022
    Review
  12. Article
  13. Predicting epitopes for vaccine development using bioinformatics tools.Therapeutic advances in vaccines and immunotherapy · 2022
    Review
  14. CD8Frontiers in immunology · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Peptides: Prospects for Use in the Treatment of COVID-19.Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Murat TopuzoĞullariDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0003-4435-7776
Tayfun AcarDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0001-5006-8167
Pelin Pelİt ArayiciDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0002-7176-4484
Burcu UÇarDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0002-8540-7832
Erennur UĞurelDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0002-5504-660X
Emrah Şefik AbamorDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0002-9174-4528
Tülin ArasoĞluDepartment of Molecular Biology and Genetics, Faculty of Arts and Science, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0001-6858-7045
Dilek Turgut-BalikDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0003-2417-4104
Serap DermanDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, İstanbul Turkey.ORCID https://orcid.org/0000-0002-6662-6642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 is a new member of the coronavirus family and caused the pandemic of coronavirus disease 2019 (COVID-19) in 2020. It is crucial to design and produce an effective vaccine for the prevention of rapid transmission and possible deaths wcaused by the disease. Although intensive work and research are being carried out all over the world to develop a vaccine, an effective and approved formulation that can prevent the infection and limit the outbreak has not been announced yet. Among all types of vaccines, epitope-based peptide vaccines outshine with their low-cost production, easy modification in the structure, and safety. In this review, vaccine studies against COVID-19 have been summarized and detailed information about the epitope-based peptide vaccines against COVID-19 has been provided. We have not only compared the peptide vaccine with other types of vaccines but also presented comprehensive literature information about development steps for an effective and protective formulation to give an insight into on-going peptide vaccine studies against SARS-CoV-2.

Indexed as

adjuvantCOVID-19epitope-based peptide vaccine designimmunoinformaticsSARS-CoV-2

Identifiers

PMID32595358
PMCPMC7314509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.