ArticleBMJ open2020
Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A Core Outcome Set to evaluate the impact of prognostication in people living with advanced cancer: An international consensus study.PloS one · 2026Pooled it
- The range and suitability of outcome measures used in the assessment of palliative treatment for inoperable malignant bowel obstruction: A systematic review.Palliative medicine · 2022Pooled it
- Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review.Palliative medicine · 2022Pooled it
- Palliative surgery: state of the science and future directions.The British journal of surgery · 2024Article
- Developing a Core Outcome Set for Prognostic Research in Palliative Cancer Care: Protocol for a Mixed Methods Study.JMIR research protocols · 2023Article
- High-quality phase 3 studies do not support the use of somatostatin analogues to reduce vomiting in malignant bowel obstruction.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Challenges to delivering evidence-based palliative medicine.Clinical medicine (London, England) · 2023Review
- Development of a Core Outcome Set for the research and assessment of inoperable malignant bowel obstruction.PloS one · 2023Article
- Current management of malignant bowel obstructions: a survey of acute care surgeons and surgical oncologists.Trauma surgery & acute care open · 2021Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
introductionStudies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, current outcome measures focus mainly on measurable physiological parameters which may not correlate strongly with patient-defined quality of life. The development of core outcome sets allows a consistent approach to evaluating clinical conditions taking into consideration patient, healthcare professional and researcher viewpoints. It follows an internationally recognised standard methodology. We present a protocol for the development of a core outcome set for Research and Assessment of MBO (RAMBO).
methodsRAMBO is a multicentre study, comprising of four phases: a systematic review to examine current scope of outcome measures associated with MBO (phase I). Interviews with patients, companions and healthcare professionals will explore priorities and preferences for care and outcomes (phase II). An expert panel meeting will collate the findings into a set of outcomes (phase III), refined by consensus through a Delphi survey with key stakeholders (phase IV). The final set of outcomes will be ratified at a consensus meeting. Each step will actively include patient partners. Thematic analysis and descriptive statistics will be used to analyse qualitative and quantitative data, respectively. ETHICS AND DISSEMINATION: Ethical approval was obtained (Wales REC 5, REF: 19/LO/1876). Study participants and relevant stakeholders will be updated with newsletters and a lay summary at the end of the study. Abstracts will be submitted to national and international conferences, result papers will be submitted to peer-reviewed, open access journals. TRIAL AND PROSPERO REGISTRATION NUMBERS: Core Outcome Measures in Effectiveness Trials (1402); Systematic Literature Review (CRD42019150648); Rapid Review (CRD42020176393).
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