Evidence map›Paper›PMID 32595130›Full record

ArticleBMJ case reports2020

Bone marrow involvement with Merkel cell carcinoma.

Ahmad Khan, Shahroz Adil, Oscar C Estalilla, Steven Jubelirer

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ahmad KhanWest Virginia University Robert C Byrd Health Sciences Center Charleston Division, Charleston, West Virginia, USA drahmadk83@gmail.com.ORCID http://orcid.org/0000-0002-7743-7740
Shahroz AdilMercy Health Saint Mary's, Grand Rapids, Michigan, USA.
Oscar C EstalillaCharleston Area Medical Center, Charleston, West Virginia, USA.
Steven JubelirerCharleston Area Medical Center, Charleston, West Virginia, USA.
Charleston Area Medical Center · USTrinity Health Grand Rapids · USWest Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Merkel cell carcinoma (MCC) is a rare but highly aggressive cutaneous tumour. Most tumours occur in the head and neck, extremities or torso and 36% of them involve the face. Bone marrow involvement in MCC is rare and to our knowledge only nine cases reported in the English literature. Bone marrow biopsy is not usually performed to stage MCC; thus, the true incidence of bone marrow involvement may be under-reported. The majority of the cases reported in the literature have some form of immunosuppression, which suggests a strong association. We report a case of extensive bone marrow involvement from MCC in an 80-year-old Caucasian woman with a history of rheumatoid arthritis treated with adalimumab, methotrexate and prednisone. It may be prudent to include bone marrow biopsy in the staging of MCC in immune-compromised patients.

Indexed as

Aged, 80 and overArthritis, RheumatoidBone MarrowBone Marrow ExaminationBone Marrow NeoplasmsCarcinoma, Merkel CellFemaleHumansImmunocompromised HostImmunosuppression TherapyNeoplasm StagingSkin Neoplasmscarcinogenesisskin cancer

Identifiers

PMID32595130
PMCPMC7322327
OpenAlexW3037762453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.