Evidence map›Paper›PMID 32595066›Full record

ReviewTrends in biochemical sciences2020

Location, Location, Location: Compartmentalization of NAD

Xiaolu A Cambronne, W Lee Kraus

Open access · greenAbstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Peripheral Neuropathy in Metabolic Stress.International journal of molecular sciences · 2026
    Review
  5. Pyrroloquinoline Quinone and NADPharmaceuticals (Basel, Switzerland) · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. NADCell reports · 2026
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Mitochondrial NMNAT3 reduces amyloid aggregates inMitochondrial communications · 2026
    Article
  17. Review
  18. Article
  19. NADCells · 2025
    Review
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Xiaolu A CambronneDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: lulu@austin.utexas.edu.
W Lee KrausLaboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: lee.kraus@utsouthwestern.edu.
The University of Texas at Austin · USThe University of Texas Southwestern Medical Center · US

Funding

The Role of PARP-1 in Hormone-Regulated TranscriptionR01DK069710 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI KRAUS, WILLIAM LEE · 2004 to 2025
$7.9M
Gatekeepers of Mitochondrial NAD+DP2GM126897 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI CAMBRONNE, XIAOLU ANG · 2017 to 2021
$2.4M
NIDDK NIH HHS R01 DK069710NIGMS NIH HHS DP2 GM126897
6 · The paper itself

Abstract

The numerous biological roles of NAD

Indexed as

Cell CompartmentationAnimalsNADSignal TransductionSubcellular FractionsNADCD38nicotinamide mononucleotide adenylyltransferase (NMNAT)nicotinamide phosphoribosyltransferase (NAMPT)poly(ADP-ribose) polymerase (PARP)sirtuin

Identifiers

PMID32595066
PMCPMC7502477
OpenAlexW3037844642

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.