Evidence map›Paper›PMID 32594836›Full record

ArticleEpigenetics2020

Relationship between redox potential of glutathione and DNA methylation level in liver of newborn guinea pigs.

Angela Mungala Lengo, Clémence Guiraut, Ibrahim Mohamed, Jean-Claude Lavoie

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  7. Narrative Review ofNutrients · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Angela Mungala LengoDepartment of Nutrition, Université De Montréal, CHU Sainte-Justine , Montréal, QC, Canada.
Clémence GuirautDepartment of Paediatrics, CHU Sainte-Justine, Université De Montréal , Montréal, QC, Canada.ORCID 0000-0002-7828-6067
Ibrahim MohamedDepartment of Nutrition, Université De Montréal, CHU Sainte-Justine , Montréal, QC, Canada.ORCID 0000-0002-9860-0279
Jean-Claude LavoieDepartment of Nutrition, Université De Montréal, CHU Sainte-Justine , Montréal, QC, Canada.ORCID 0000-0002-5910-0300
Centre Hospitalier Universitaire Sainte-Justine · CA

Funding

CIHR PJT-148522
6 · The paper itself

Abstract

The metabolism of DNA methylation is reported to be sensitive to oxidant molecules or oxidative stress. Hypothesis: early-life oxidative stress characterized by the redox potential of glutathione influences the DNA methylation level. The

Indexed as

DNA MethylationOxidative StressAnimalsDNA (Cytosine-5-)-MethyltransferasesEmulsionsFish OilsGlutathioneGuinea PigsLiverMaleOlive OilParenteral NutritionPhospholipidsSoybean OilTriglyceridesDNA (Cytosine-5-)-MethyltransferasesEmulsionsFish OilsGlutathioneOlive OilPhospholipidsSMOFlipidSoybean Oilsoybean oil, phospholipid emulsionTriglyceridesDNA methylationintralipidneonatal nutritionoxidative stressparenteral nutritionSMOFLipid

Identifiers

PMID32594836
PMCPMC7678935
OpenAlexW3037585378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.