Evidence map›Paper›PMID 32594815›Full record

ReviewImmunotherapy2020

The immunotherapy revolution in genitourinary malignancies.

Shruti U Gandhy, Ravi A Madan, Jeanny B Aragon-Ching

Open access · greenAbstract readReview
In one paragraph

Review in Immunotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shruti U GandhyGenitourinary Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0001-8981-6775
Ravi A MadanGenitourinary Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0001-5106-8636
Jeanny B Aragon-ChingGU Medical Oncology, Inova Schar Cancer Institute, Fairfax, VA, USA.ORCID 0000-0002-6714-141X
National Institutes of Health · USGTx (United States) · US

Funding

Evaluation of novel treatments in biochemically recurrent prostateZIABC011896 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MADAN, RAVI · 2019 to 2025
$3.6M
6 · The paper itself

Abstract

Immune checkpoint inhibitor (ICI) therapy and therapeutic cancer vaccines have continued to demonstrate survival benefit and durable clinical response in patients with renal cell cancer, prostate cancer and bladder cancer, with limited responses in testicular cancer. The role of immunotherapy in combination with chemotherapy or other targeted therapies in the neo-adjuvant, adjuvant and metastatic setting is actively being explored. We describe the current immunotherapy-related treatment modalities approved for genitourinary cancers, focusing on immune checkpoint inhibitors, vaccines and other modalities, and highlight ongoing studies involving immunotherapy in these cancer types.

Indexed as

AnimalsAntineoplastic AgentsB7-H1 AntigenCancer VaccinesCTLA-4 AntigenHumansImmune Checkpoint InhibitorsImmunotherapyProgrammed Cell Death 1 ReceptorUrogenital NeoplasmsAntineoplastic AgentsB7-H1 AntigenCancer VaccinesCTLA-4 AntigenImmune Checkpoint InhibitorsPdcd1 protein, mouseProgrammed Cell Death 1 Receptorbladder cancerCTLA-4genitourinary malignanciesimmune checkpoint inhibitorsPD-1PD-L1prostate cancerrenal cell carcinomatesticular cancervaccines

Identifiers

PMID32594815
PMCPMC7466927
OpenAlexW3037565490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.