ArticleHypertension (Dallas, Tex. : 1979)2020
Long-Term Blood Pressure Variability in Young Adulthood and Coronary Artery Calcium and Carotid Intima-Media Thickness in Midlife: The CARDIA Study.
Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Predictors of long-term absence of coronary artery calcium in individuals with high blood pressure: results from the MESA study.Annals of medicine · 2023Trial
- Synchronous wearable ultrasound for early detection of coronary and carotid artery comorbidity.Science advances · 2026Article
- Long-term Blood Pressure Exposure and Cerebral Microbleeds: a Retrospective Study from the META-KLS Cohort.Clinical neuroradiology · 2025Article
- Relationship Between Subclinical Renal Damage and Maximum Rate of Blood Pressure Variation Assessed by Fourier Analysis of 24-h Blood Pressure Curve in Patients with Essential Hypertension.Life (Basel, Switzerland) · 2025Article
- Determinants and Clinical Impact of Visit-to-visit Blood Pressure Variability in Patients with Heart Failure with Preserved Ejection Fraction.JMA journal · 2025Article
- Blood Pressure Variability and Risk of Cardiovascular Events and Mortality in Real-World Clinical Settings.Journal of the American Heart Association · 2025Article
- Blood pressure variability: a review.Journal of hypertension · 2025Review
- Association of systolic blood pressure time in target range with carotid atherosclerotic plaque and carotid intima-media thickness in hypertensive patients.Scientific reports · 2025Article
- Assessment of blood pressure variability: characteristics and comparison of blood pressure measurement methods.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Associations of Dietary Calcium and Phosphorus With Vascular and Valvular Calcification: The ARIC Study.JACC. Advances · 2024Article
- Association between Systolic Blood Pressure Variability and Incident Aortic Stenosis.Journal of clinical medicine · 2024Article
- Relationship between 24 h blood pressure variability and mortality in acute myocardial infarction patients.Clinical cardiology · 2024Article
- Evaluating Total Atherosclerosis Burden of Baroreceptor-Resident Arteries after Ischemic Cerebrovascular Disease for Identifying Patients with Heavy Coronary Atherosclerosis Burden.Journal of atherosclerosis and thrombosis · 2024Article
- The essential role of dual-energy x-ray absorptiometry in the prediction of subclinical cardiovascular disease.Frontiers in cardiovascular medicine · 2024Review
- Blood Pressure in Children in the 21st Century: What Do We Know and Where Do We Go From Here?Hypertension (Dallas, Tex. : 1979) · 2023Review
- Imaging Early Life Cardiovascular Phenotype.Circulation research · 2023Review
- Short- to long-term blood pressure variability: Current evidence and new evaluations.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- Inter-arm systolic blood pressure difference: non-persistence and association with incident cardiovascular disease in the Multi-ethnic Study of Atherosclerosis.Journal of human hypertension · 2023Article
- Visit-to-visit variability of blood pressure and risk of macrovascular and microvascular complications in patients with type 2 diabetes: A Chinese primary-care cohort study.Journal of diabetes · 2022Article
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Authors and funding
14 authors.
Funding
Abstract
Recent evidence links long-term (visit-to-visit) blood pressure (BP) variability to the risk of cardiovascular disease, independent of mean BP levels. Potential associations between long-term BP variability and cardiovascular disease risk may be reflected in early life course alterations in coronary artery calcium (CAC) and carotid intima-media thickness. We evaluated 2482 CARDIA study (Coronary Artery Risk Development in Young Adults) participants (mean [SD] age at the year 20 exam [2005-2006] was 45.4 [3.6] years, 43.2% men, and 41.3% black). We included participants with BP assessments across 20-years (year 0, 2, 5, 7, 10, 15, 20 exams) and carotid intima-media thickness and CAC data at the year 20 exam. BP variability was assessed using variability independent of the mean and SD. Adjusted multivariable linear or logistic regression models (as appropriate) were used to assess associations between long-term BP variability measures and carotid intima-media thickness. and CAC (ln [CAC+1] and prevalent CAC). Long-term systolic BP variability independent of the mean (per 1 SD) was positively associated with carotid intima-media thickness (β=10 μm, SE=3,
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