Evidence map›Paper›PMID 32594738›Full record

ArticleJournal of agricultural and food chemistry2020

Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in

Minhao Xie, Jun Yang, Jianan Zhang, Heather L Sherman, Zhenyu Zhang, Lisa M Minter, Bruce D Hammock, Yeonhwa Park, Guodong Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. The metabolic nature of inflammatory bowel diseases.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Minhao XieCollaborative Innovation Center for Modern Grain Circulation and Safety, and College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing 210023, China.ORCID http://orcid.org/0000-0002-3876-3439
Jun YangDepartment of Entomology and Nematology, and UC Davis Comprehensive Cancer Center, University of California, Davis, California 95616, United States.
Jianan ZhangDepartment of Food Science, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Heather L ShermanDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Zhenyu ZhangDepartment of Food Science, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Lisa M MinterDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Bruce D HammockDepartment of Entomology and Nematology, and UC Davis Comprehensive Cancer Center, University of California, Davis, California 95616, United States.ORCID http://orcid.org/0000-0003-1408-8317
Yeonhwa ParkDepartment of Food Science, University of Massachusetts, Amherst, Massachusetts 01003, United States.ORCID http://orcid.org/0000-0001-9727-0899
Guodong ZhangDepartment of Food Science, University of Massachusetts, Amherst, Massachusetts 01003, United States.ORCID http://orcid.org/0000-0001-7780-5470
University of Massachusetts Amherst · USUC Davis Comprehensive Cancer CenterNanjing University of Finance and Economics · CN

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
Supplement for bioactive lipids as effectors and indicators of the deleterious effects of human healthR35ES030443 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MORISSEAU, CHRISTOPHE HP · 2019 to 2025
$5.8M
Prevention of obesity-enhanced colorectal cancer via targeting soluble epoxide hydrolaseR03CA237795 · NCI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI DECKER, ERIC · 2019 to 2020
$147k
Prevention of colorectal cancer via targeting CYP epoxygenasesR03CA218520 · NCI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ZHANG, GUODONG · 2018 to 2019
$147k
NCI NIH HHS R03 CA218520NCI NIH HHS R03 CA237795NIEHS NIH HHS P42 ES004699NIEHS NIH HHS R35 ES030443
6 · The paper itself

Abstract

Dietary intake of linoleic acid (LA, 18:2ω-6) has risen dramatically in recent decades. Previous studies have suggested a high intake of LA could increase tissue concentrations of proinflammatory and protumorigenic ω-6-series eicosanoid metabolites, increasing risks of inflammation and associated diseases. However, the effects of a LA-rich diet on in vivo profiles of eicosanoids and development of inflammatory diseases are understudied. Here, we treated spontaneous colitis-prone (

Indexed as

AnimalsColitisEicosanoidsHumansInterleukin-10Linoleic AcidLiverMaleMiceMice, KnockoutEicosanoidsIL10 protein, mouseInterleukin-10Linoleic Acidcolitiscolonic inflammationeicosanoidsIl-10−/− micelinoleic acid

Identifiers

PMID32594738
PMCPMC7901524
OpenAlexW3037777453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.