Evidence map›Paper›PMID 32594614›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Type 3 innate lymphoid cells are associated with a successful intestinal transplant.

Jiman Kang, Katrina Loh, Leonid Belyayev, Priscilla Cha, Mohammed Sadat, Khalid Khan, Yuriy Gusev, Krithika Bhuvaneshwar, Habtom Ressom, Sangeetha Moturi and 7 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Chimerism-Mediated Tolerance in Intestinal Transplantation.Gastroenterology clinics of North America · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  14. Ischemia reperfusion injury facilitates lung allograft acceptance through IL-33-mediated activation of donor-derived IL-5 producing group 2 innate lymphoid cells.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  15. Dual JAK2/Aurora kinase A inhibition prevents human skin graft rejection by allo-inactivation and ILC2-mediated tissue repair.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  16. Article
  17. Article
  18. Stem Cell Therapy and Innate Lymphoid Cells.Stem cells international · 2022
    Review
  19. Review
  20. EfficientFrontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Jiman KangCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Katrina LohCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Leonid BelyayevCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Priscilla ChaCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Mohammed SadatCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Khalid KhanCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Yuriy GusevInnovation Center for Biomedical Informatics (ICBI), Georgetown University Medical Center, Washington, District of Columbia, USA.
Krithika BhuvaneshwarInnovation Center for Biomedical Informatics (ICBI), Georgetown University Medical Center, Washington, District of Columbia, USA.
Habtom RessomLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, USA.
Sangeetha MoturiCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Jason KaiserCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Jason HawksworthCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Simon C RobsonDepartments of Anesthesiology and Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Cal S MatsumotoCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Michael ZasloffCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Thomas M FishbeinCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Alexander KroemerCenter for Translational Transplant Medicine, Georgetown University Medical Center, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.ORCID 0000-0002-9842-4973
Georgetown University · USBeth Israel Deaconess Medical Center · USChildren's National · US

Funding

UPIT: Unleash the Potential of Intestinal TransplantationR01AI132389 · NIAID · GEORGETOWN UNIVERSITY · PI KROEMER, ALEXANDER HELMUT KURT · 2017 to 2021
$2.4M
NIAID NIH HHS R01 AI132389
6 · The paper itself

Abstract

Although innate lymphoid cells (ILCs) play fundamental roles in mucosal barrier functionality and tissue homeostasis, ILC-related mechanisms underlying intestinal barrier function, homeostatic regulation, and graft rejection in intestinal transplantation (ITx) patients have yet to be thoroughly defined. We found protective type 3 NKp44

Indexed as

Immunity, InnateLymphocytesCytokinesHumansInterferon-gammaIntestinesCytokinesInterferon-gammabasic (laboratory) research/scienceimmunobiologyinnate immunityintestinal (allograft) function/dysfunctionintestine/multivisceral transplantationischemia-reperfusion injury (IRI)mucosal immunityrejectiontranslational research/science

Identifiers

PMID32594614
PMCPMC8049507
OpenAlexW3037345378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.