Evidence map›Paper›PMID 32594606›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Early national and center-level changes to kidney transplantation in the United States during the COVID-19 epidemic.

Brian J Boyarsky, William A Werbel, Christine M Durand, Robin K Avery, Kyle R Jackson, Amber B Kernodle, Jon Snyder, Ryutaro Hirose, Indraneel M Massie, Jacqueline M Garonzik-Wang and 2 more

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  10. OPTN/SRTR 2021 Annual Data Report: COVID-19.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  11. Article
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  13. Review
  14. Review
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  17. OPTN/SRTR 2020 Annual Data Report: COVID.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  18. Article
  19. Solid organ transplantations and COVID-19 disease.World journal of transplantation · 2021
    Review
  20. COVID-19 Legacy.Southern medical journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Brian J BoyarskyDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-6902-9854
William A WerbelDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-2943-5895
Christine M DurandDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-2605-9257
Robin K AveryDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-7692-3619
Kyle R JacksonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-8135-5377
Amber B KernodleDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-6459-5280
Jon SnyderScientific Registry of Transplant Recipients, Minneapolis, Minnesota, USA.ORCID 0000-0001-7974-8940
Ryutaro HiroseDepartment of Surgery, University of California, San Francisco, California, USA.
Indraneel M MassieOxford College of Emory University, Oxford, Georgia, USA.
Jacqueline M Garonzik-WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-1924-4801
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-5288-5125

Funding

RESEARCH TRAINING IN MICROBIAL DISEASEST32AI007291 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JOEL N BLANKSON, Sara Elizabeth Cosgrove · 1986 to 2026
$9.1M
Clinical and Laboratory Research Training for Gastrointestinal SurgeonsT32DK007713 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI DAVID J HACKAM · 1996 to 2026
$5.2M
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
The effect of socioeconomic status and environment characteristics on disparate postdonation health outcomes between Black and White living kidney donorsF32DK117563 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI KERNODLE, AMBER · 2018 to 2020
$240k
Differential Survival Benefit of Incompatible Living Donor Kidney Transplantation: Modeling Outcomes for Different Patient PhenotypesF32DK113719 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI JACKSON, KYLE R · 2017 to 2019
$238k
NIAID NIH HHS T32 AI007291NIDDK NIH HHS F32 DK113719NIDDK NIH HHS F32DK113719NIDDK NIH HHS F32 DK117563NIDDK NIH HHS F32DK117563NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K01DK101677NIDDK NIH HHS K24 DK101828NIDDK NIH HHS K24DK101828NIDDK NIH HHS T32 DK007713NIDDK NIH HHS T32DK007713
6 · The paper itself

Abstract

In March 2020, coronavirus disease 2019 (COVID-19) spread rapidly nationally, causing widespread emergent changes to the health system. Our goal was to understand the impact of the epidemic on kidney transplantation (KT), at both the national and center levels, accounting statistically for waitlist composition. Using Scientific Registry of Transplant Recipients data, we compared data on observed waitlist registrations, waitlist mortality, and living-donor and deceased-donor kidney transplants (LDKT/DDKT) March 15-April 30, 2020 to expected events calculated from preepidemic data January 2016-February 2020. There were few changes before March 15, at which point the number of new listings/DDKT/LDKT dropped to 18%/24%/87% below the expected value (all P < .001). Only 12 centers performed LDKT March 15-31; by April 30, 40 centers had resumed LDKT. The decline in new listings and DDKT was greater among states with higher per capita confirmed COVID-19 cases. The number of waitlist deaths was 2.2-fold higher than expected in the 5 states with highest COVID-19 burden (P < .001). DCD DDKT and regional/national imports declined nationwide but most steeply in states with the highest COVID-19 burden. The COVID-19 epidemic has resulted in substantial changes to KT; we must adapt and learn rapidly to continue to provide safe access to transplantation and limit the growing indirect toll of an already deadly disease.

Indexed as

PandemicsRegistriesSARS-CoV-2AdolescentAdultAgedChildChild, PreschoolComorbidityCOVID-19FemaleGraft SurvivalHumansInfantInfant, NewbornKidney Transplantationclinical research/practicedonors and donation: deceaseddonors and donation: livinghealth services and outcomes researchinfection and infectious agents - viralinfectious diseasekidney transplantation/nephrologyorgan transplantation in generalpatient survivalregistry/registry analysis

Identifiers

PMID32594606
PMCPMC7361931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.