ArticleEnvironmental science and pollution research international2020
Oxidative stress, hemato-immunological, and intestinal morphometry changes induced by ochratoxin A in APRI rabbits and the protective role of probiotics.
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- The protective influence of orange essential oil nano-emulsion on growth performance, antioxidant activity, immune status, inflammatory response, and hepato-renal function in heat-stressed growing rabbits.Tropical animal health and production · 2026Article
- Lactobacillus plantarum and Lactobacillus acidophilus enhance growth performance, immunity, cecal microbiota, and vital organs histomorphology in rabbits.Scientific reports · 2026Article
- Dietary probiotic supplementation withAnimal biotechnology · 2025Article
- Effects of a multi-strain probiotic on productive traits, antioxidant defence, caecal microbiota and short‑chain fatty acid profile, and intestinal histomorphology in rabbits.Animal bioscience · 2025Article
- An overview of mycotoxicoses in rabbits.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Review
- Risks for animal health related to the presence of ochratoxin A (OTA) in feed.EFSA journal. European Food Safety Authority · 2023Article
- Effects of embryo injected with ochratoxins A on hatching quality and jejunum antioxidant capacity of ducks at hatching.Frontiers in veterinary science · 2022Article
- Effects ofFrontiers in veterinary science · 2022Article
- The Influence of Chicken Egg Lysozyme or Zinc-Bacitracin Antibiotic on the Growth Performance, Antibacterial Capacity, Blood Profiles, and Antioxidative Status of Rabbits: A Comparative Study.Animals : an open access journal from MDPI · 2021Article
- Review
- Enhancing the Growth Rate, Biochemical Blood Indices, and Antioxidative Capacity of Broilers by IncludingFrontiers in veterinary science · 2020Article
- The Influence of Dietary Chicken Egg Lysozyme on the Growth Performance, Blood Health, and Resistance AgainstFrontiers in veterinary science · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
This work studied the protective effects of Aspergillus awamori against ochratoxin A (OTA)-induced toxicity in APRI maternal line rabbits. A total number of 48 APRI line weanling rabbits (5 weeks) were divided into 4 groups (12 rabbits each) and fed the basal diet, 30 ppb/kg diet of OTA, 1 g/kg diet of A. awamori, and a mixture of OTA and A. awamori for 8 weeks. OTA reduced the final body weight and weight gain as well as the intestinal villi length and thickness, whereas increased the feed intake and feed conversion ratio. Rabbits fed diets with OTA showed significantly reduced crude protein, lipids, and fibers apparent digestibility coefficients (P < 0.05). The red blood cells and hemoglobin were significantly decreased in the OTA group comparing with the other groups (P < 0.05). The blood total protein and albumin displayed significantly lower levels by OTA than the other groups. In contrast, glucose, aspartate aminotransferase (AST), alkaline phosphatase (ALP), urea, and creatinine levels were significantly increased by OTA (P < 0.05). Phagocytic activity (PA) and phagocytic index (PI) showed significantly (P < 0.05) decreased levels in OTA-contaminated group, while rabbits fed A. awamori significantly showed the highest PA and PI levels (P < 0.05). Dietary A. awamori kept the levels of PA and PI in rabbits fed OTA significantly higher than those fed without A. awamori (P < 0.05) and not significantly different from the control group (P > 0.05). Catalase (CAT) and superoxide dismutase (SOD) displayed significantly lower levels in the OTA group, while malondialdehyde (MDA) was significantly higher than the other groups (P < 0.05). Rabbits fed OTA-contaminated diets displayed significantly lower CAT and SOD and higher MDA than rabbits fed OTA combined with A. awamori (P < 0.05). Our results indicated that dietary A. awamori ameliorated the damage in APRI rabbits fed OTA through alleviation of oxidative stress and immunity.
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