Evidence map›Paper›PMID 32594239›Full record

ArticleParasitology research2020

Common occurrence of Cryptosporidium hominis in children attending day-care centers in Medellin, Colombia.

Ana Luz Galvan-Diaz, Katherine Bedoya-Urrego, Angelica Medina-Lozano, Johanna Uran-Velasquez, Juan F Alzate, Gisela Garcia-Montoya

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Frontiers in microbiology · 2025
    Pooled it
  2. Prevalence of human cryptosporidiosis in the Americas: systematic review and meta-analysis.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022
    Pooled it
  3. Article
  4. Article
  5. Cryptosporidiosis outbreak in Amazonia, French Guiana, 2018.PLoS neglected tropical diseases · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ana Luz Galvan-DiazGrupo de Microbiología ambiental, Escuela de microbiología, Universidad de Antioquia, Ciudad universitaria, Bloque 5-410. Cl. 67 #53-108, Medellín, Antioquia, Colombia. ana.galvan@udea.edu.co.ORCID https://orcid.org/0000-0002-2127-4209
Katherine Bedoya-UrregoCentro Nacional de Secuenciación Genómica-CNSG, Sede de Investigación Universitaria-SIU, Universidad de Antioquia, Cra 53#61-30 Torre 1 Lab S2-15, Medellín, Antioquia, Colombia.
Angelica Medina-LozanoGrupo de Parasitología, Facultad de Medicina, Corporación Académica para el Estudio de las Patologías Tropicales, Universidad de Antioquia, Cra. 51d #62-29, Medellín, Antioquia, Colombia.
Johanna Uran-VelasquezCentro Nacional de Secuenciación Genómica-CNSG, Sede de Investigación Universitaria-SIU, Universidad de Antioquia, Cra 53#61-30 Torre 1 Lab S2-15, Medellín, Antioquia, Colombia.
Juan F AlzateCentro Nacional de Secuenciación Genómica-CNSG, Sede de Investigación Universitaria-SIU, Universidad de Antioquia, Cra 53#61-30 Torre 1 Lab S2-15, Medellín, Antioquia, Colombia.
Gisela Garcia-MontoyaCentro Nacional de Secuenciación Genómica-CNSG, Sede de Investigación Universitaria-SIU, Universidad de Antioquia, Cra 53#61-30 Torre 1 Lab S2-15, Medellín, Antioquia, Colombia.
Universidad de Antioquia · CO

Funding

Colciencias Project ID 1115-777-57608
6 · The paper itself

Abstract

Cryptosporidium spp. are apicomplexan protozoa associated with chronic diarrhea in AIDS and other immunocompromised patients, and one of the commonest causes of childhood diarrhea and malnutrition, particularly in low-income settings. In Colombia, there are few molecular epidemiological studies on Cryptosporidium spp.; thereby, the transmission dynamics of this parasite in the country is poorly known. This study evaluated the diversity of Cryptosporidium at species, subtype family, and subtype level in children attending various day-care centers in Medellin, Colombia. Two hundred and ninety stool samples from children < 5 years of age were collected from April to November of 2015. All samples were processed by PCR and sequence analysis of the ssu RNA gene and the gp60 gene. An infection rate of 2.4% was observed, with only two Cryptosporidium species identified: C. hominis (6/7) and C. meleagridis (1/7). Cryptosporidium hominis isolates belonged to the subtypes IbA10G2, IaA13R6 and IaA13R7; IIIbA26G1R1 C. meleagridis subtype was also detected. There is a C. hominis predominance in the children evaluated, suggesting an important role of the anthroponotic transmission cycle in the day-care centers analyzed. Further investigation is required to determine infection sources and susceptible hosts in order to define appropriate management of cryptosporidiosis.

Indexed as

AdolescentAnimalsChildChild CareChild, PreschoolColombiaCryptosporidiosisCryptosporidiumDiarrheaDNA, ProtozoanFecesFemaleGenotypeHumansHygieneMaleDNA, ProtozoanSulfotransferases60-kDa glycoprotein (gp60) geneColombiaCryptosporidium spp.Speciesssu rRNA geneSubtypes

Identifiers

PMID32594239
OpenAlexW3037747390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.