Evidence map›Paper›PMID 32594220›Full record

ReviewRheumatology international2020

Current understanding and future perspectives of brain-heart-kidney axis in psoriatic arthritis.

George Markousis-Mavrogenis, Michael T Nurmohamed, Loukia Koutsogeorgopoulou, Theodoros Dimitroulas, Gikas Katsifis, Vasiliki Vartela, Dimos Mitsikostas, Genovefa Kolovou, Maria Tektonidou, Paraskevi Voulgari and 3 more

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Rheumatology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

George Markousis-MavrogenisOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.ORCID http://orcid.org/0000-0001-8192-6670
Michael T NurmohamedDepartment of Rheumatology and Immunology Center, VUMC, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9989-737X
Loukia KoutsogeorgopoulouDepartment of Pathophysiology, Laikon Hospital, Athens, Greece.
Theodoros DimitroulasFourth Department of Internal Medicine, School of Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloníki, Greece.ORCID http://orcid.org/0000-0002-0364-1642
Gikas KatsifisNaval Hospital, Athens, Greece.ORCID http://orcid.org/0000-0002-3214-7416
Vasiliki VartelaOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.ORCID http://orcid.org/0000-0002-2907-8237
Dimos Mitsikostas1st Neurology Department, Medical School, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0002-4691-3388
Genovefa KolovouOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.
Maria TektonidouKapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0003-2238-0975
Paraskevi VoulgariRheumatology Department, University of Ioannina, Ioannina, Greece.ORCID http://orcid.org/0000-0002-9383-5722
Petros P SfikakisKapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0001-5484-2930
George D KitasArthritis Research UK Epidemiology Unit, Manchester University, Manchester, UK.ORCID http://orcid.org/0000-0002-0828-6176
Sophie I MavrogeniOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece. soma13@otenet.gr.ORCID http://orcid.org/0000-0003-1089-7766
National and Kapodistrian University of Athens · GROnassis Cardiac Surgery Center · GRAmsterdam UMC Location Vrije Universiteit Amsterdam · NLAristotle University of Thessaloniki · GRAthens Naval & Veterans Hospital · GRLaiko General Hospital of Athens · GRUniversity of Ioannina · GRUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriatic arthritis (PsA) patients are at a higher risk of systemic inflammatory sequelae, leading to microalbuminuria, cardiovascular (CVD) and neuropsychiatric (NPD) disease. Our aim is to present the existing literature about the relationship between CVD, kidney and NPD in PsA. The literature evaluation of PsA revealed that chronic T-cell activation and increased levels of circulating immune complexes can cause glomerular injury leading to microalbuminuria, which predicts CVD and all-cause mortality in both diabetic and non-diabetic patients. Furthermore, it is a marker of preclinical brain damage and identifies patients at higher risk of NPD/CVD events. Among the currently used imaging modalities in PsA, magnetic resonance imaging (MRI) maintains a crucial role, because it is ideal for concurrent evaluation of brain/heart involvement and serial follow up assessment. There is increasing evidence regarding the relationship between kidneys, heart and brain in PsA. Although currently there are no official recommendations about a combined brain/heart MRI in PsA, it could be considered in PsA with microalbuminuria, arrhythmia, HF, cognitive dysfunction and/or depression.

Indexed as

Arthritis, PsoriaticCardiovascular DiseasesCentral Nervous System DiseasesEchocardiographyFemaleHumansKidney DiseasesMagnetic Resonance ImagingMalePositron Emission Tomography Computed TomographyArrhythmiaCardiovascular diseaseCardiovascular magnetic resonance imagingCentral nervous system diseaseCentral nervous system magnetic resonance imagingCognitive dysfunctionDepressionHeart failurePsoriatric arthritis

Identifiers

PMID32594220
OpenAlexW3037605605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.