Observational studyRheumatology international2020
Trends in idiopathic inflammatory myopathies: cross-sectional data from the German National Database.
Observational study in Rheumatology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- The health-related quality of life, mental health and mental illnesses of patients with inclusion body myositis (IBM): results of a mixed methods systematic review.Orphanet journal of rare diseases · 2022Pooled it
- Clinicopathological and serological spectrum of idiopathic inflammatory myopathies: Experience from a neuromuscular referral center in Cyprus.Journal of neuromuscular diseases · 2026Article
- Pre-screening of endomysial microvessel density by fast random forest image processing machine learning algorithm accelerates recognition of a modified vascular network in idiopathic inflammatory myopathies.Diagnostic pathology · 2025Article
- Uncovering the link between inflammatory rheumatic diseases and male reproductive health: a perspective on male infertility and sexual dysfunction.Rheumatology international · 2024Review
- [Rheumatological care in Germany : Memorandum of the German Society for Rheumatology and Clinical Immunology 2024].Zeitschrift fur Rheumatologie · 2024Article
- Sleep Disorders in Connective Tissue Diseases-Coexisting Diseases or Disease Components?Journal of clinical medicine · 2024Review
- Fatigue and sleep quality in Chinese adults with connective tissue disease: A cross-sectional study.Sleep & breathing = Schlaf & Atmung · 2024Article
- Pulmonary Hypertension Associated with Anti-synthetase Syndrome: A Case Report and Literature Review.Internal medicine (Tokyo, Japan) · 2023Review
- Inclusion body myositis-health-related quality of life and care situation during phases of the "patience journey" in Germany: results from a qualitative study.Health and quality of life outcomes · 2023Article
- Healthcare utilization and unmet needs of patients with antisynthetase syndrome: An international patient survey.Rheumatology international · 2023Article
- [With RheMIT rheumatology centers can participate in the German national database-Expansion of the long-term rheumatological documentation].Zeitschrift fur Rheumatologie · 2023Article
- Patient-Reported Health-Related Quality of Life, Anxiety and Depression in Patients with Inclusion Body Myositis: A Register-Based Cross-Sectional Study in Germany.Journal of clinical medicine · 2023Article
- Article
- Myositis in Germany: epidemiological insights over 15 years from 2005 to 2019.Neurological research and practice · 2022Article
- Investigating characteristics of idiopathic inflammatory myopathy flares using daily symptom data collected via a smartphone app.Rheumatology (Oxford, England) · 2022Article
- Article
- [Clinical and immunological characteristics of 88 cases of overlap myositis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021Article
- Pericardial effusion in idiopathic inflammatory myopathies: A cross-sectional study from Asia and review of the literature.International journal of immunopathology and pharmacologyReview
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe trends in outcomes among patients with idiopathic inflammatory myopathies (IIM) over two decades.
methodsFrom 1997 to 2017, a total of 1079 IIM patients were documented in the National Database of the German Collaborative Arthritis Centers. Annual cross-sectional data on treatment, disease activity, patient-reported outcomes, hospitalization and employment were compared across the years. Information on phenotypes, organ manifestations and autoantibodies was collected for a subset to compare the assessment of global health, pain, fatigue and sleeping disorders.
resultsIn 2017, significantly more IIM patients were assessed to be in low disease activity (94%) than in 1997 (59%), p < 0.01. Pain (p = 0.001), global health (p = 0.049), fatigue (p = 0.03) and sleeping disorders (p = 0.01) also improved since recording. Glucocorticoid use decreased from 84 to 58% (p < 0.01). Employment in patients < 65 years remained unchanged (53%), while early retirement (23-9%), hospitalization/year (34-18%) and sick leave (52-24%) decreased. A total of 186 patients with information on subtypes were classified as polymyositis (44%), dermatomyositis (33%), anti-synthetase syndrome (10%), overlapping-myositis (8%), inclusion body myositis (2%), necrotizing myositis (0.5%) and unspecific (3%). The most frequently reported symptoms were limitations in global health (60%), fatigue (57%) and sleeping disorders (51%), and all of them were most frequent in overlap-myositis. Pulmonary hypertension and cardiomyopathy were associated with poor outcomes regarding global health, daily activities and fatigue.
conclusionIIM patients report better outcomes than 20 years ago, along with good physician-reported disease control. Global health, fatigue and sleeping disorders are relevant patient-reported domains in IIM.
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