Evidence map›Paper›PMID 32593972›Full record

ArticleDrug and alcohol dependence2020

Age disparities in six-month treatment retention for opioid use disorder.

Carrie M Mintz, Ned J Presnall, John M Sahrmann, Jacob T Borodovsky, Paul E A Glaser, Laura J Bierut, Richard A Grucza

Erratum issuedAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Review
  8. An Assertive Community Intervention to Engage Youth with Opioid Use Disorder and Their Families.Child and adolescent psychiatric clinics of North America · 2024
    Review
  9. Article
  10. Article
  11. Retention in Telehealth Treatment for Opioid Use Disorder Among Rural Populations: A Retrospective Cohort Study.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Carrie M MintzDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA. Electronic address: mintzc@wustl.edu.
Ned J PresnallDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
John M SahrmannDepartment of Internal Medicine at Washington University School of Medicine, St Louis, MO, USA.
Jacob T BorodovskyDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Paul E A GlaserDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Laura J BierutDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Richard A GruczaDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JAY Arnold TISCHFIELD · 1989 to 2026
$162.7M
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSET32DA007261 · NIDA · WASHINGTON UNIVERSITY · PI ARPANA AGRAWAL, Jose A Moron-Concepcion · 1991 to 2026
$8.8M
Washington University Career Development Program in Drug Abuse and AddictionK12DA041449 · NIDA · WASHINGTON UNIVERSITY · PI Laura J. Bierut, Patricia A Cavazos-Rehg · 2017 to 2026
$4.2M
Nicotine Dependence to Smoking Cessation: Sequencing Common and Rare VariantsR01DA036583 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2014 to 2017
$3.0M
WASHINGTON UNIVERSITY COMPARATIVE EFFECTIVENESS ADMINISTRATIVE DATA REPOSITORYR24HS019455 · AHRQ · WASHINGTON UNIVERSITY · PI FRASER, VICTORIA J. · 2010 to 2010
$969k
AN EXAMINATION OF AGE-RELATED DISPARITIES IN MEDICATION ASSISTED TREATMENT AND ASSOCIATED OUTCOMESR21DA044744 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2017 to 2018
$419k
USING TEMPORAL VARIATION IN RISK BEHAVIOR TO UNDERSTAND TRENDS IN ADOLESCENT ALCOHOL MISUSER21AA025689 · NIAAA · WASHINGTON UNIVERSITY · PI GRUCZA, RICHARD A · 2018 to 2019
$416k
Assessing the Contribution of Alcohol and Psychotropic Medication Use to Upward US Injury and Poisoning TrendsF32AA027941 · NIAAA · WASHINGTON UNIVERSITY · PI BORODOVSKY, JACOB T · 2019 to 2020
$94k
AHRQ HHS R24 HS019455NCATS NIH HHS UL1 TR002345NIAAA NIH HHS F32 AA027941NIAAA NIH HHS R21 AA025689NIAAA NIH HHS U10 AA008401NIA NIH HHS U24 AG021886NIDA NIH HHS K12 DA041449NIDA NIH HHS R01 DA036583NIDA NIH HHS R21 DA044744NIDA NIH HHS T32 DA007261
6 · The paper itself

Abstract

BACKGROUND AND

aimsAdolescents with opioid use disorder (OUD) are an understudied and vulnerable population. We examined the association between age and six-month treatment retention, and whether any such association was moderated by medication treatment.

methodsIn this retrospective cohort study, we used an insurance database with OUD treatment claims from 2006-2016. We examined 261,356 OUD treatment episodes in three age groups: adolescents (ages 12-17), young adults (18-25) and older adults (26-64). We used logistic regression to estimate prevalence of six-month retention before and after stratification by treatment type (buprenorphine, naltrexone, or psychosocial only). Insurance differences (commercial vs Medicaid) in medication treatment prevalence were also assessed.

resultsAdolescents were less likely to be retained compared to adults (17.6 %; 95 % CI 16.5-18.7 % for adolescents; 25.1 %; 95 % CI 24.7-25.4 % for young adults; 33.3 %; 95 % CI 33.0-33.5 % for older adults). This disparity was reduced after adjusting for treatment type. For all ages, buprenorphine was more strongly associated with retention than naltrexone or psychosocial treatment. Adolescents who received buprenorphine were more than four times as likely to be retained in treatment (44.8 %; 95 % CI 40.6-49.0) compared to those who received psychosocial services (9.7 %; 95 % CI 8.8-10.8). Persons with commercial insurance were more likely to receive medication than those with Medicaid (73 % vs 36 %, (χ

conclusionsAge disparities in six-month treatment retention are strongly related to age disparities in medication treatment. Results point to need for improved implementation of medication treatment for persons with OUD, regardless of age or insurance status.

Indexed as

AdolescenceAge disparityBuprenorphineInsurance disparityNaltrexoneOpioid use disorderTreatment retention

Identifiers

PMID32593972
PMCPMC7903941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.