Evidence map›Paper›PMID 32593950›Full record

ArticlePsychiatry research. Neuroimaging2020

Examination of preliminary behavioral and effective connectivity findings from treatment response to citalopram in cocaine use disorder: A dynamic causal modeling study.

A D Snyder, E Zuniga, L Ma, J L Steinberg, K Woisard, P A Narayana, S Lane, J Schmitz, F G Moeller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research. Neuroimaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A D SnyderInstitute for Drug and Alcohol Studies; Department of Psychiatry. Electronic address: asnyder2@vcu.edu.
E ZunigaInstitute for Drug and Alcohol Studies.
L MaInstitute for Drug and Alcohol Studies; Department of Radiology.
J L SteinbergInstitute for Drug and Alcohol Studies; Department of Psychiatry.
K WoisardInstitute for Drug and Alcohol Studies; Virginia Commonwealth University School of Medicine, Richmond, VA, United States.
P A NarayanaDepartment of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, TX, United States.
S LaneProgram in Neuroscience, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, Texas, United States.
J SchmitzFaillace Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, Texas, United States.
F G MoellerInstitute for Drug and Alcohol Studies; Department of Psychiatry; Department of Pharmacology and Toxicology; Department of Neurology, Virginia Commonwealth University, Richmond, VA, United States. Electronic address: frederick.moeller@vcuhealth.org.

Funding

Translational MR Imaging in Cocaine Pharmacotherapy DevelopmentP50DA009262 · NIDA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MOELLER, FREDERICK GERARD · 1994 to 2014
$26.9M
Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
MRS: NEUROLOGICAL DVMT &DISORDERS: LEARNING, READING, COGNITIVE, APHASIA, DYSLES10RR019186 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NARAYANA, PONNADA A · 2004 to 2004
$500k
Research Colloquium for Junior InvestigatorsR13DA042568 · NIDA · AMERICAN PSYCHIATRIC ASSOC FOUNDATION · PI CLARKE, DIANA ELAINE · 2017 to 2019
$75k
NCATS NIH HHS UL1 TR002649NCRR NIH HHS S10 RR019186NIDA NIH HHS P50 DA009262NIDA NIH HHS R13 DA042568
6 · The paper itself

Abstract

We sought effective (directional) connectivity parameters associated with response to citalopram in cocaine use disorder (CUD) by conducting a functional magnetic resonance imaging (fMRI) experiment with participants diagnosed with CUD (n = 13) and matched healthy controls (HC; n = 17). CUD participants showed a positive correlation between bilateral DLPFC-to-putamen effective connectivity and treatment effectiveness score. These preliminary results support further investigation of prefrontal-striatal interactions in response to treatment in CUD.

Indexed as

AdultCitalopramCocaine-Related DisordersCorpus StriatumFemaleHumansImpulsive BehaviorMagnetic Resonance ImagingMaleNerve NetPrefrontal CortexSelective Serotonin Reuptake InhibitorsTreatment OutcomeYoung AdultCitalopramSelective Serotonin Reuptake InhibitorsCitalopramCocaine use disorderEffective connectivityImpulsivitySelective serotonin reuptake inhibitorSsri

Identifiers

PMID32593950
PMCPMC8948471

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.