ReviewHeart & lung : the journal of critical care
A review of cardiac manifestations and predictors of outcome in patients with COVID - 19.
Review in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- A systematic review and meta-analysis of regional risk factors for critical outcomes of COVID-19 during early phase of the pandemic.Scientific reports · 2021Pooled it
- Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis.BMC infectious diseases · 2020Pooled it
- The Role of Hand-Held Cardiac Ultrasound in Patients with COVID-19.Biomedicines · 2023Review
- Association between pre-existing cardiovascular disease, mortality and cardiovascular outcomes in hospitalised patients with COVID-19.Frontiers in cardiovascular medicine · 2023Article
- Association of the human platelet antigens polymorphisms with platelet count in patients with COVID-19.Frontiers in medicine · 2023Article
- A Review of Cardiovascular Complications among Pregnant Patients with COVID-19.Reviews in cardiovascular medicine · 2022Review
- Article
- Infective endocarditis and COVID -19 coinfection: An updated review.Acta bio-medica : Atenei Parmensis · 2022Review
- Associations of pre-existing cardiovascular morbidity with severity and the fatality rate in COVID-19 patients: a systematic review and meta-analysis.Osong public health and research perspectives · 2022Article
- Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia.Frontiers in cardiovascular medicine · 2022Article
- Cardio-cerebrovascular complications in COVID-19 patients: A retrospective cohort study.Frontiers in medicine · 2022Article
- Antiviral activity of molnupiravir against COVID-19: a schematic review of evidences.Bulletin of the National Research Centre · 2022Review
- Prognostic significance of CHADSJournal of cardiovascular and thoracic research · 2022Article
- The Potential Impact of COVID-19 Virus on the Heart and the Circulatory System.Infection and drug resistance · 2022Review
- Clinical considerations for critically ill COVID-19 cancer patients: A systematic review.World journal of clinical cases · 2021Article
- In-hospital clinical complications of COVID-19: a brief overview.Future virology · 2021Article
- Clinical features and mortality in COVID-19 SARI versus non COVID-19 SARI cases from Western Rajasthan, India.Journal of family medicine and primary care · 2021Article
- Global burden of acute myocardial injury associated with COVID-19: A systematic review, meta-analysis, and meta-regression.Annals of medicine and surgery (2012) · 2021Review
- Different SARS-CoV-2 haplotypes associate with geographic origin and case fatality rates of COVID-19 patients.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021Article
- Classification and analysis of outcome predictors in non-critically ill COVID-19 patients.Internal medicine journal · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronavirus disease (COVID-19) pandemic has so far involved 184 countries and more than 2.79 million patients worldwide. Over the past three months, it has attributed to more than 196,000 deaths, with more than 50,000 deaths in the United States alone. Pulmonary manifestations are predominant and have been well identified. Cardiac involvement is also common. Acute cardiac injury, the most common cardiac manifestation of this disease can be seen in patients even without prior cardiac comorbidities. Established cardiovascular risk factors such as diabetes mellitus, hypertension, and coronary artery disease predispose to cardiac injury, the severity of illness and mortality. Non-ischemic myocardial injury secondary to cytokine storm is thought to be the predominant mechanism of acute cardiac injury associated with COVID-19. Multiple mechanisms and processes contribute to cardiac injury resulting in a poor outcome. Some of these are not clearly understood. Clinical and diagnostic details of cardiovascular involvement in these patients are mostly limited to biochemical markers. Multiple therapeutic agents have been tried with questionable efficacy and without clinical evidence. Interactions of comorbidities, cardiovascular drugs, the cardiac effect of therapeutic agents on the illness continue to be under investigation. With an increasing number of patients, newer promising therapies, and ongoing clinical trials, the exact mechanisms and extent to which these risk factors contribute to outcomes will be clearer in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.