ArticleJournal of neurodevelopmental disorders2020
Expressive language development in adolescents with Down syndrome and fragile X syndrome: change over time and the role of family-related factors.
Article in Journal of neurodevelopmental disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- The relationship between language and executive functions in adolescents with Down syndrome and fragile X syndrome.Journal of neurodevelopmental disorders · 2026Article
- Planning for the Transition to Adulthood: Parent Perspectives on the Planning Process and Experiences of Young Adults with Fragile X Syndrome.Advances in neurodevelopmental disorders · 2026Article
- Beyond the Fragile X protein: neighborhood characteristics explain individual differences in IQ and adaptive behaviors of Fragile X syndrome.Frontiers in psychiatry · 2025Article
- Narrative microstructure and macrostructure in adolescents with Down syndrome and Williams syndrome.Frontiers in psychology · 2025Article
- Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome.Journal of autism and developmental disorders · 2024Article
- The impact of social-environmental factors on IQ in syndromic intellectual developmental disabilities.Journal of clinical and translational science · 2024Review
- The association between expressive language skills and adaptive behavior in individuals with Down syndrome.Scientific reports · 2022Article
- Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models.Cell reports · 2022Article
- Pragmatic Profiles of Adults with Fragile X Syndrome and Williams Syndrome.Brain sciences · 2022Article
- Brief Report: Linguistic Mazes and Perseverations in School-Age Boys with Fragile X Syndrome and Autism Spectrum Disorder and Relationships with Maternal Maze Use.Journal of autism and developmental disorders · 2022Article
- Communication in fragile X syndrome: Patterns and implications for assessment and intervention.Frontiers in psychology · 2022Review
- Considerations for measuring individual outcomes across contexts in Down syndrome: Implications for research and clinical trials.International review of research in developmental disabilities · 2022Article
- Using telehealth-delivered procedures to collect a parent-implemented expressive language sampling narrative task in monolingual and bilingual families with Autism Spectrum Disorder: A pilot study.Frontiers in rehabilitation sciences · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
backgroundIt is well known that individuals with Down syndrome (DS) or fragile X syndrome (FXS) demonstrate expressive language difficulties beginning early in childhood. It is less clear, however, whether expressive language skills change during the adolescent period in these individuals, and if any of these changes are syndrome specific. Studying this, as well as the role of maternal and family-related factors in expressive language development, may provide the foundation for efficacious interventions for adolescents with DS or FXS.
methodsIn this study, we examined expressive language trajectories, assessed through conversation and narration, in 57 adolescent males with intellectual disability (ID) (20 DS and 37 FXS) in relation to the diagnostic group (DS vs. FXS) and family-related factors (maternal IQ, maternal psychological distress, closeness in the mother-child relationship, family income, and maternal and paternal education) after adjusting for chronological age (CA) and nonverbal cognition.
resultsChanges over repeated annual assessments for males with DS or FXS were observed only during conversation, such as an increase in talkativeness, but a decrease in syntax complexity and lexical diversity. We found a diagnosis-related effect in the change over time in conversational talkativeness favoring those with FXS. Finally, a closer mother-child relationship predicted less decrease over time in lexical diversity during conversation, and participants of mothers who graduated college showed a greater increase in conversational talkativeness over time compared to those of mothers with a high school education.
conclusionsOur results suggest that, during the adolescent period for males with DS or FXS, there is an increase in the amount of talk produced in conversational contexts, but also a decrease in the quality of the language produced. In addition, our results indicate syndrome-specificity for aspects of expressive language development and reinforce the protective role of family-related factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.