ArticleThe Plant journal : for cell and molecular biology2020
Plant breeding involving genetic engineering does not result in unacceptable unintended effects in rice relative to conventional cross-breeding.
Article in The Plant journal : for cell and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Transcriptome and nutritional composition analysis of stacked transgenic maize with insect resistance and herbicide tolerance.GM crops & food · 2025Article
- Genetically modified soybean lines exhibit less transcriptomic variation compared to natural varieties.GM crops & food · 2023Article
- Coronatine-Induced Maize Defense againstJournal of fungi (Basel, Switzerland) · 2023Article
- Effect of T-DNA Integration on Growth of TransgenicInternational journal of molecular sciences · 2023Article
- Effects of stacking breeding on the methylome and transcriptome profile of transgenic rice with glyphosate tolerance.Planta · 2023Article
- Analysis of the Genetic Stability of Insect and Herbicide Resistance Genes in Transgenic Rice Lines: A Laboratory and Field Experiment.Rice (New York, N.Y.) · 2023Article
- Comparison of the Phenotypic Performance, Molecular Diversity, and Proteomics in Transgenic Rice.Plants (Basel, Switzerland) · 2022Article
- Proteomic and Metabolomic Evaluation of Insect- and Herbicide-Resistant Maize Seeds.Metabolites · 2022Article
- Transcriptomic Analysis of Mature Transgenic Poplar Expressing the Transcription FactorFrontiers in bioengineering and biotechnology · 2022Article
- RNA Interference-Based Genetic Engineering Maize Resistant toFrontiers in plant science · 2022Article
- Modified Gene Editing Systems: Diverse Bioengineering Tools and Crop Improvement.Frontiers in plant science · 2022Review
- Cooperative herbivory between two important pests of rice.Nature communications · 2021Article
- Metabolic Analysis RevealsMetabolites · 2021Article
- Compositional equivalence assessment of insect-resistant genetically modified rice using multiple statistical analyses.GM crops & food · 2021Article
- Integrated proteomics and metabolomics analysis of transgenic and gene-stacked maize line seeds.GM crops & food · 2021Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advancements in -omics techniques provide powerful tools to assess the potential effects in composition of a plant at the RNA, protein and metabolite levels. These technologies can thus be deployed to assess whether genetic engineering (GE) causes changes in plants that go beyond the changes introduced by conventional plant breeding. Here, we compare the extent of transcriptome and metabolome modification occurring in leaves of four GE rice lines expressing Bacillus thuringiensis genes developed by GE and seven rice lines developed by conventional cross-breeding. The results showed that both types of crop breeding methods can bring changes at transcriptomic and metabolic levels, but the differences were comparable between the two methods, and were less than those between conventional non-GE lines were. Metabolome profiling analysis found several new metabolites in GE rice lines when compared with the closest non-GE parental lines, but these compounds were also found in several of the conventionally bred rice lines. Functional analyses suggest that the differentially expressed genes and metabolites caused by both GE and conventional cross-breeding do not involve detrimental metabolic pathways. The study successfully employed RNA-sequencing and high-performance liquid chromatography mass spectrometry technology to assess the unintended changes in new rice varieties, and the results suggest that GE does not cause unintended effects that go beyond conventional cross-breeding in rice.
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