Evidence map›Paper›PMID 32592998›Full record

ReviewiScience2020

Transmissible Cancers in an Evolutionary Perspective.

Antoine M Dujon, Robert A Gatenby, Georgina Bramwell, Nick MacDonald, Erin Dohrmann, Nynke Raven, Aaron Schultz, Rodrigo Hamede, Anne-Lise Gérard, Mathieu Giraudeau and 2 more

Abstract readReview
In one paragraph

Review in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Wildlife Trade and Genetic Basis of Disease Susceptibility: A Review.International journal of immunogenetics · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Approaches and methods to study wildlife cancer.The Journal of animal ecology · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Antoine M DujonDeakin University, Geelong, School of Life and Environmental Sciences, Centre for Integrative Ecology, Waurn Ponds, Vic 3216, Australia.
Robert A GatenbyDepartment of Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
Georgina BramwellDeakin University, Geelong, School of Life and Environmental Sciences, Centre for Integrative Ecology, Waurn Ponds, Vic 3216, Australia.
Nick MacDonaldDeakin University, Geelong, School of Life and Environmental Sciences, Centre for Integrative Ecology, Waurn Ponds, Vic 3216, Australia.
Erin DohrmannDeakin University, Geelong, School of Life and Environmental Sciences, Centre for Integrative Ecology, Waurn Ponds, Vic 3216, Australia.
Nynke RavenDeakin University, Geelong, School of Life and Environmental Sciences, Centre for Integrative Ecology, Waurn Ponds, Vic 3216, Australia.
Aaron SchultzDeakin University, Geelong, School of Life and Environmental Sciences, Centre for Integrative Ecology, Waurn Ponds, Vic 3216, Australia.
Rodrigo HamedeSchool of Natural Sciences, University of Tasmania, Private Bag 55, Hobart, TAS 7001, Australia.
Anne-Lise GérardCREEC, UMR IRD 224-CNRS 5290-Université de Montpellier, Montpellier, France.
Mathieu GiraudeauCREEC, UMR IRD 224-CNRS 5290-Université de Montpellier, Montpellier, France.
Frédéric ThomasCREEC, UMR IRD 224-CNRS 5290-Université de Montpellier, Montpellier, France.
Beata UjvariDeakin University, Geelong, School of Life and Environmental Sciences, Centre for Integrative Ecology, Waurn Ponds, Vic 3216, Australia; School of Natural Sciences, University of Tasmania, Private Bag 55, Hobart, TAS 7001, Australia. Electronic address: beata.ujvari@deakin.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inter-individual transmission of cancer cells represents an intriguing and unexplored host-pathogen system, with significant ecological and evolutionary ramifications. The pathogen consists of clonal malignant cell lines that spread horizontally as allografts and/or xenografts. Although only nine transmissible cancer lineages in eight host species from both terrestrial and marine environments have been investigated, they exhibit evolutionary dynamics that may provide novel insights into tumor-host interactions particularly in the formation of metastases. Here we present an overview of known transmissible cancers, discuss the necessary and sufficient conditions for cancer transmission, and provide a comprehensive review on the evolutionary dynamics between transmissible cancers and their hosts.

Indexed as

Biological SciencesCancerEvolutionary BiologyEvolutionary Ecology

Identifiers

PMID32592998
PMCPMC7327844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.