Evidence map›Paper›PMID 32592278›Full record

ArticleGenes, chromosomes & cancer2020

Frequency and prognostic impact of PAX5 p.P80R in pediatric acute lymphoblastic leukemia patients treated on an AIEOP-BFM acute lymphoblastic leukemia protocol.

Mareike Jung, Maximilian Schieck, Winfried Hofmann, Marcel Tauscher, Jana Lentes, Anke Bergmann, Marie Stelter, Anja Möricke, Julia Alten, Brigitte Schlegelberger and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Genes, chromosomes & cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. PAX Family, Master Regulator in Cancer.Diagnostics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Genetic alterations in lymphoblastic leukaemiaMedizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2024
    Article
  9. Cancers · 2024
    Article
  10. Novel Biomarkers and Molecular Targets in ALL.Current hematologic malignancy reports · 2024
    Review
  11. Frontiers in oncology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in oncology · 2022
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Mareike JungDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.ORCID 0000-0003-0728-8695
Maximilian SchieckDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.ORCID 0000-0001-5878-0546
Winfried HofmannDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Marcel TauscherDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Jana LentesDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Anke BergmannDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Marie StelterDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Anja MörickeDepartment of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.
Julia AltenDepartment of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.
Brigitte SchlegelbergerDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Martin SchrappeDepartment of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.
Martin ZimmermannPediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.
Martin StanullaPediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.
Gunnar CarioDepartment of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.
Doris SteinemannDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.ORCID 0000-0001-8797-0816
Medizinische Hochschule Hannover · DEUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PAX5 is a member of the paired box (PAX) family of transcription factors involved in B-cell development. PAX5

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsAsparaginaseBiomarkers, TumorCyclophosphamideCytarabineDaunorubicinGene FrequencyHumansMercaptopurineMethotrexateMutation, MissensePAX5 Transcription FactorPrecursor Cell Lymphoblastic Leukemia-LymphomaPrednisoneVincristineAsparaginaseBiomarkers, TumorCyclophosphamideCytarabineDaunorubicinMercaptopurineMethotrexatePAX5 protein, humanPAX5 Transcription FactorPrednisoneVincristineacute lymphoblastic leukemiaAIEOP-BFM ALLB-cell precursor ALLPAX5pediatric acute lymphoblastic leukemia

Identifiers

PMID32592278
PMCPMC7540392
OpenAlexW3037488872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.