ArticleJournal of clinical laboratory analysis2020
Development of a sensitive HPLC-MS/MS method for 25-hydroxyvitamin D
Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Accuracy of Capillary Blood for Assessing Vitamin A Nutritional Status Among Children Under 7 Years of Age: A Multicenter Study.Maternal & child nutrition · 2025Article
- Menstrual Blood as a Non-Invasive Alternative for Monitoring Vitamin Levels.Journal of clinical medicine · 2024Article
- Associations between Longitudinal Maternal and Cord Blood Vitamin D Status and Child Growth Trajectories Up to 4 Years of Age.Nutrients · 2024Article
- Correlation and consistency between two detection methods for serum 25 hydroxyvitamin D levels in human venous blood and capillary blood.Frontiers in nutrition · 2024Article
- Maternal and neonatal blood vitamin D status and neurodevelopment at 24 months of age: a prospective birth cohort study.World journal of pediatrics : WJP · 2023Article
- Association between Suboptimal 25-Hydroxyvitamin D Status and Overweight/Obesity in Infants: A Prospective Cohort Study in China.Nutrients · 2022Article
- Associations between maternal vitamin D status during three trimesters and cord blood 25(OH)D concentrations in newborns: a prospective Shanghai birth cohort study.European journal of nutrition · 2021Article
- Development of a sensitive HPLC-MS/MS method for 25-hydroxyvitamin DJournal of clinical laboratory analysis · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMeasurement of 25-hydroxyvitamin D [25(OH)D)] levels is important. The current method requires a relatively large volume of serum. To minimize the amount of serum needed, we established a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method to measure 25(OH)D in capillary serum.
methodsVenous blood and fingertip blood were collected from 90 participants. Volumes of 100 µL of venous serum and 20 µL of capillary serum were collected. The serum samples were pretreated by protein removal, extraction and concentration, and an HPLC-MS/MS method based on chromatographic separation and multi reactive ion monitoring was conducted. The intra- and inter-batch variation coefficients were less than 10% for both 25-hydroxyvitamin D
resultsThe limit of detection (LOD) of 25(OH)D
conclusionsThis capillary blood method requires minimal sample preparation and is suitable for routine use in the 25(OH)D detection.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.