Evidence map›Paper›PMID 32592197›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2020

Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin.

Marilena Crescente, Paul C Armstrong, Nicholas S Kirkby, Matthew L Edin, Melissa V Chan, Fred B Lih, Jing Jiao, Tania Maffucci, Harriet E Allan, Charles A Mein and 6 more

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. FLife (Basel, Switzerland) · 2021
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Marilena CrescenteCentre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Paul C ArmstrongCentre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nicholas S KirkbyNational Heart & Lung Institute, Imperial College London, London, UK.
Matthew L EdinDivision of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Melissa V ChanCentre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Fred B LihDivision of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Jing JiaoDepartment of Medical and Molecular Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Tania MaffucciCentre for Cell Biology and Cutaneous Research, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Harriet E AllanCentre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Charles A MeinCentre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Carles Gaston-MassuetCentre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Graeme S CottrellReading School of Pharmacy and ICMR, University of Reading, Reading, UK.
Jane A MitchellNational Heart & Lung Institute, Imperial College London, London, UK.
Darryl C ZeldinDivision of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Harvey R HerschmanDepartment of Medical and Molecular Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Timothy D WarnerCentre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0003-3988-4408
Queen Mary University of London · GBNational Institute of Environmental Health Sciences · USImperial College London · GBUniversity of California, Los Angeles · USReading Museum · GB

Funding

Characterization And Functional Significance Of P450 Arachidonate EpoxygenasesZIAES025034 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$18.6M
Mass Spectrometry QuantitationZICES103005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WILLIAMS, JASON · 2018 to 2025
$9.2M
P450 Arachidonate EpoxygenasesZ01ES025034 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 1995 to 2008
$2.2M
British Heart Foundation FS/16/1/31699British Heart Foundation PG/15/79/31777British Heart Foundation PG/17/40/33028Intramural NIH HHS Z01 ES025034Intramural NIH HHS Z99 ES999999
6 · The paper itself

Abstract

Aspirin prevents thrombosis by inhibiting platelet cyclooxygenase (COX)-1 activity and the production of thromboxane (Tx)A

Indexed as

AnimalsArachidonic AcidAspirinBlood PlateletsCyclooxygenase 1Cyclooxygenase InhibitorsEicosanoidsFemaleMaleMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutThrombosisArachidonic AcidAspirinCyclooxygenase 1Cyclooxygenase InhibitorsEicosanoidsMembrane ProteinsPtgs1 protein, mouseantithrombotic therapyaspirineicosanoid profilingendotheliumplatelets

Identifiers

PMID32592197
PMCPMC9359103
OpenAlexW3028113930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.