Evidence map›Paper›PMID 32592157›Full record

Observational studyClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2021

Spanish multicenter study of surgical resection of pancreatic tumors infiltrating the celiac axis: does the type of pancreatectomy affect results?

J M Ramia, E de Vicente, F Pardo, L Sabater, S Lopez-Ben, Y Quijano, T Villegas, G Blanco-Fernandez, L Diez-Valladares, I Lopez-Rojo and 6 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

J M RamiaDepartment of Surgery, Hospital General Universitario de Alicante, Pintor Baeza, 11, 03010, Alacant, Alacant, Spain. jose_ramia@hotmail.com.ORCID http://orcid.org/0000-0003-1186-953X
E de VicenteDepartment of Surgery, Hospital Universitario HM Sanchinarro, Madrid, Spain.
F PardoDepartment of Surgery, Clínica Universitaria de Navarra, Pamplona, Spain.
L SabaterDepartment of Surgery, Hospital Clínico, Biomedical Research Institute, University of Valencia, Valencia, Spain.
S Lopez-BenDepartment of Surgery, Hospital Josep Trueta, Girona, Spain.
Y QuijanoDepartment of Surgery, Hospital Universitario HM Sanchinarro, Madrid, Spain.
T VillegasDepartment of Surgery, Hospital Virgen de las Nieves, Granada, Spain.
G Blanco-FernandezDepartment of Surgery, Hospital Universitario Infanta Cristina, Badajoz, Spain.
L Diez-ValladaresDepartment of Surgery, Hospital Universitario Clínico San Carlos, Madrid, Spain.
I Lopez-RojoDepartment of Surgery, Fundación Jimenez Diaz, Madrid, Spain.
E Martin-PerezDepartment of Surgery, Hospital Universitario La Princesa, Madrid, Spain.
F PereiraDepartment of Surgery, Hospital Universitario de Fuenlabrada, Fuenlabrada, Spain.
A J GonzalezDepartment of Surgery, Hospital Quirón Málaga, Malaga, Spain.
J HerreraDepartment of Surgery, Complejo Hospitalario de Navarra, Pamplona, Spain.
M I García-DomingoDepartment of Surgery, Hospital Mutua de Terrassa, Terrassa, Spain.
M SerradillaDepartment of Surgery, Hospital Universitario Miguel Servet, Zaragoza, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatectomy plus celiac axis resection (CAR) is performed in patients with locally advanced pancreatic cancer. The morbidity rates are high, and no survival benefit has been confirmed. It is not known at present whether it is the type of pancreatectomy, or CAR itself, that is the reason for the high complication rates.

methodsObservational retrospective multicenter study. INCLUSION CRITERIA: patient undergoing TP, PD or DP plus CAR for a pancreatic cancer.

resultsSixty-two patients who had undergone pancreatic cancer surgery (PD,TP or DP) plus CAR were studied. Group 1: 17 patients who underwent PD/TP-CAR (13TP/4PD); group 2: 45 patients who underwent DP-CAR. Groups were mostly homogeneous. Operating time was longer in the PD/TP group, while operative complications did not differ statistically in the two groups. The number of lymph nodes removed was higher in the PD/TP group (26.5 vs 17.3), and this group also had a higher positive node ratio (17.9% vs 7.6%). There were no statistical differences in total or disease-free survival between the two groups.

conclusionIt seems that CAR, and not the type of pancreatectomy, influences morbidity and mortality in this type of surgery. International multicenter studies with larger numbers of patients are now needed to validate the data presented here.

Indexed as

Body Mass IndexCeliac ArteryDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateLymph Node ExcisionMaleMiddle AgedNeoplasm InvasivenessOperative TimePancreatectomyPancreatic NeoplasmsPostoperative ComplicationsRetrospective StudiesSpainArterialCancerDistal pancreatectomyDP-CAREmbolizationPancreasPancreatoduodenectomyPHAEReviewSurgeryTotal pancreatectomy

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.