Evidence map›Paper›PMID 32591966›Full record

ReviewDigestive diseases and sciences2021

LncRNA: A Potential Research Direction in Intestinal Barrier Function.

Zhi-Feng Jiang, Lin Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Zhi-Feng JiangCenter of Emergency and Intensive Care Unit, Jinshan Hospital of Fudan University, Medical Research Center for Chemical Injury of Fudan University, No. 1508 Longhang Road, Shanghai, 201508, China.
Lin ZhangCenter of Emergency and Intensive Care Unit, Jinshan Hospital of Fudan University, Medical Research Center for Chemical Injury of Fudan University, No. 1508 Longhang Road, Shanghai, 201508, China. linzhang0315@fudan.edu.cn.ORCID 0000-0002-0950-7145
Fudan University · CNJinshan Hospital of Fudan University · CN

Funding

National Natural Science Foundation of China No. 81801943Science and Technology Commission of Shanghai Municipality no. 18411970200
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides and play important roles in a variety of diseases. LncRNAs are involved in many biologic processes including cell differentiation, development, and apoptosis. The intestinal barrier is considered one of the most important protective barriers in humans. Severe damage or dysfunction of the intestinal barrier may be associated with the occurrence and development of many diseases, such as inflammatory bowel disease and ulcerative colitis. LncRNAs have been found to be associated with intestinal barrier function in some studies, which are at an early stage. In this review, we introduce the roles of LncRNAs in the intestinal barrier and investigate the possibility of lncRNAs as a research field in the intestinal barrier.

Indexed as

AnimalsGene Expression RegulationHumansInflammatory Bowel DiseasesIntestinal MucosaPermeabilityRNA, Long NoncodingRNA, Long NoncodingBiogenesisInflammatory bowel diseaseIntestinal barrierIntestinal barrier dysfunctionLncRNAUlcerative colitis

Identifiers

PMID32591966
OpenAlexW3037411860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.