Evidence map›Paper›PMID 32591643›Full record

ArticleLeukemia2020

A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models.

Siebe Loontiens, Suzanne Vanhauwaert, Lisa Depestel, Givani Dewyn, Wouter Van Loocke, Finola E Moore, Elaine G Garcia, Lance Batchelor, Chiara Borga, Barbara Squiban and 8 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Genomic landscape of T-cell lymphoblastic lymphoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2022
    Article
  4. Zebrafish models of acute leukemias: Current models and future directions.Wiley interdisciplinary reviews. Developmental biology · 2021
    Review
  5. Frontiers in oncology · 2021
    Review
  6. PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation.Frontiers in cell and developmental biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Siebe LoontiensDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0002-4602-4580
Suzanne VanhauwaertDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Lisa DepestelDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Givani DewynDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Wouter Van LoockeDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Finola E MooreDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.
Elaine G GarciaDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.
Lance BatchelorSection of Pediatric Hematology-Oncology, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Chiara BorgaSection of Pediatric Hematology-Oncology, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Barbara SquibanSection of Pediatric Hematology-Oncology, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Megan Malone-PerezSection of Pediatric Hematology-Oncology, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Pieter-Jan VoldersDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0002-2685-2637
Volodimir OlexioukDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Pieter Van VlierbergheDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0001-9063-7205
David M LangenauDepartment of Pathology, Massachusetts General Hospital Research Institute, Boston, MA, 02114, USA.ORCID http://orcid.org/0000-0001-6664-8318
J Kimble FrazerSection of Pediatric Hematology-Oncology, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA.
Kaat Durinck *Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. Kaat.durinck@ugent.be.ORCID http://orcid.org/0000-0003-1762-5739
Frank Speleman *Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0002-6628-8559

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI David W Dyer · 2012 to 2026
$60.2M
Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
Oncogenic pathways and therapeutic targets in T cell acute lymphoblastic leukemiaR01CA211734 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LANGENAU, DAVID MICHAEL · 2017 to 2021
$1.9M
NCI NIH HHS P30 CA225520NCI NIH HHS R01 CA211734NIGMS NIH HHS P20 GM103447
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsComparative Genomic HybridizationGene Transfer TechniquesGenomicsHomeodomain ProteinsLeukemia-Lymphoma, Adult T-CellPrecursor T-Cell Lymphoblastic Leukemia-LymphomaProto-Oncogene ProteinsZebrafishHomeodomain ProteinsProto-Oncogene Proteins

Identifiers

PMID32591643
PMCPMC7906429

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.