Trial reportScientific reports2020
Effects of combining constraint-induced movement therapy and action-observation training on upper limb kinematics in children with unilateral cerebral palsy: a randomized controlled trial.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- A systematic review of instrumented assessments for upper limb function in cerebral palsy: current limitations and future directions.Journal of neuroengineering and rehabilitation · 2024Pooled it
- [Effectiveness of mirror therapy and action observation therapy in infantile cerebral palsy: a systematic review].Anales del sistema sanitario de Navarra · 2022Pooled it
- Bimanual coordination in children with unilateral cerebral palsy: Effects of short- and intensive bimanual training on spatiotemporal characteristics.Human movement science · 2026Article
- Review
- Defining Goal-Directed Training for Children with Cerebral Palsy: A Scoping Review and Framework for Implementation.Children (Basel, Switzerland) · 2025Review
- Action Observation for Children and Adolescents with Cerebral Palsy: Hope or Hype? A Systematic Review with Meta-Analysis.Children (Basel, Switzerland) · 2025Review
- Movement Component Analysis of Reaching Strategies in Individuals With Stroke: Preliminary Study.JMIR rehabilitation and assistive technologies · 2023Article
- Pertinence of Constraint-Induced Movement Therapy in Neurological Rehabilitation: A Scoping Review.Cureus · 2023Article
- Stereoptic serious games as a visual rehabilitation tool for individuals with a residual amblyopia (AMBER trial): a protocol for a crossover randomized controlled trial.BMC ophthalmology · 2023Article
- Detecting Movement Changes in Children with Hemiparesis after Upper Limb Therapies: A Responsiveness Analysis of a 3D Bimanual Protocol.Sensors (Basel, Switzerland) · 2023Article
- Envisioning translational hyperscanning: how applied neuroscience might improve family-centered care.Social cognitive and affective neuroscience · 2023Article
- Assessment of movement disorders using wearable sensors during upper limb tasks: A scoping review.Frontiers in robotics and AI · 2022Article
- Lower limb muscle fatigue after uphill walking in children with unilateral spastic cerebral palsy.PloS one · 2022Article
- The Effect of Constraint-Induced Movement Therapy Combined With Repetitive Transcranial Magnetic Stimulation on Hand Function in Preschool Children With Unilateral Cerebral Palsy: A Randomized Controlled Preliminary Study.Frontiers in behavioral neuroscience · 2022Article
- Effectiveness of Action Observation Training on Upper Limb Motor Function in Children with Hemiplegic Cerebral Palsy: A Systematic Review of Randomized Controlled Trials.Pediatric health, medicine and therapeutics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modified constraint-induced movement therapy (mCIMT) improves upper limb (UL) motor execution in unilateral cerebral palsy (uCP). As these children also show motor planning deficits, action-observation training (AOT) might be of additional value. Here, we investigated the combined value of AOT to mCIMT on UL kinematics in children with uCP in a randomized controlled trial. Thirty-six children with uCP completed an UL kinematic and clinical evaluation after participating in a 9-day mCIMT camp wearing a splint for 6 h/day. The experimental group (mCIMT + AOT, n = 20) received 15 h of AOT, i.e. video-observation and execution of unimanual tasks. The control group (mCIMT + placebo, n = 16) watched biological-motion free videos and executed the same tasks. We examined changes in motor control (movement duration, peak velocity, time-to-peak velocity, and trajectory straightness) and kinematic movement patterns (using Statistical Parametric Mapping) during the execution of three unimanual, relevant tasks before the intervention, after and at 6 months follow-up. Adding AOT to mCIMT mainly affected movement duration during reaching, whereas little benefit is seen on UL movement patterns. mCIMT, with or without AOT, improved peak velocity and trajectory straightness, and proximal movement patterns. Clinical and kinematic improvements are poorly related. Although there seem to be limited benefits of AOT to CIMT on UL kinematics, our results support the inclusion of kinematics to capture changes in motor control and movement patterns of the proximal joints.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.