ArticleNature communications2020
Elastomeric polyamide biomaterials with stereochemically tuneable mechanical properties and shape memory.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
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- Sequence-Structure-Property Relationships in Short-Chain Polyesters: How Primary Structure Governs Macroscopic Performance.Macromolecules · 2026Article
- Introducing Disulfide Bonds into Polyester Biomaterials via Nucleophilic Thiol-yne Polymerization.ACS macro letters · 2025Article
- Exploiting Activated Alkyne Chemistry for the Synthesis of Tailored Amphiphilic Janus Dendrimers with Aggregation-Induced Emission and Their Assemblies for Cell Imaging.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Colloidal-fibrillar composite gels demonstrate structural reinforcement, secondary fibrillar alignment, and improved vascular healing outcomes.Communications engineering · 2025Article
- Smart Biomimetic 3D Scaffolds Based on Shape Memory Polyurethane for Soft Tissue Repair.Polymers · 2025Article
- Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration.Military Medical Research · 2024Review
- An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation.Theranostics · 2024Article
- Resorbable barrier polymers for flexible bioelectronics.Nature communications · 2023Article
- The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials.Frontiers in bioengineering and biotechnology · 2023Article
- 3D-printed NIR-responsive shape memory polyurethane/magnesium scaffolds with tight-contact for robust bone regeneration.Bioactive materials · 2022Article
- Click Step-Growth Polymerization andAccounts of chemical research · 2022Article
- Sugar-Based Polymers with Stereochemistry-Dependent Degradability and Mechanical Properties.Journal of the American Chemical Society · 2022Article
- Using Stereochemistry to Control Mechanical Properties in Thiol-Yne Click-Hydrogels.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2021Article
- Using Stereochemistry to Control Mechanical Properties in Thiol-Yne Click-Hydrogels.Angewandte Chemie (International ed. in English) · 2021Article
- Click Nucleophilic Conjugate Additions to Activated Alkynes: Exploring Thiol-yne, Amino-yne, and Hydroxyl-yne Reactions from (Bio)Organic to Polymer Chemistry.Chemical reviews · 2021Review
- Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering.Nature communications · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biocompatible polymers are widely used in tissue engineering and biomedical device applications. However, few biomaterials are suitable for use as long-term implants and these examples usually possess limited property scope, can be difficult to process, and are non-responsive to external stimuli. Here, we report a class of easily processable polyamides with stereocontrolled mechanical properties and high-fidelity shape memory behaviour. We synthesise these materials using the efficient nucleophilic thiol-yne reaction between a dipropiolamide and dithiol to yield an α,β - unsaturated carbonyl moiety along the polymer backbone. By rationally exploiting reaction conditions, the alkene stereochemistry is modulated between 35-82% cis content and the stereochemistry dictates the bulk material properties such as tensile strength, modulus, and glass transition. Further access to materials possessing a broader range of thermal and mechanical properties is accomplished by polymerising a variety of commercially available dithiols with the dipropiolamide monomer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.