ArticleNature communications2020
Dynamic perceptual feature selectivity in primary somatosensory cortex upon reversal learning.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- How perceptual learning rewires brain connectivity: lessons from the visual system in a top-down perspective.Frontiers in neural circuits · 2025Pooled it
- Dynamically Updated Task Rules Reshape Sensory Processing Across Cortical Hierarchies of the Posterior Parietal Cortex and Primary Auditory Cortex.Neuroscience bulletin · 2026Article
- A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.bioRxiv : the preprint server for biology · 2026Article
- The role of transthalamic pathways in perception.Communications biology · 2026Review
- Neuronal identity is not static: An input-driven perspective.PLoS computational biology · 2025Article
- Learning-Associated Flexibility of Cortical Taste Coding Is Impaired in Shank3 Knockout Mice.bioRxiv : the preprint server for biology · 2025Article
- Learning, prediction accuracy, and neural plasticity in sensory cortex.Current opinion in neurobiology · 2025Review
- Reward history guides focal attention in whisker somatosensory cortex.Nature communications · 2025Article
- Thalamocortical feedback selectively controls pyramidal neuron excitability.Nature communications · 2025Article
- Cortical circuits for cross-modal generalization.Nature communications · 2025Article
- Quantitative dynamics of neural uncertainty in sensory processing and decision-making during discriminative learning.Experimental & molecular medicine · 2025Article
- Pallidal prototypic neuron and astrocyte activities regulate flexible reward-seeking behaviors.bioRxiv : the preprint server for biology · 2025Article
- Repetitive Sensory Stimulation Potentiates and Recruits Sensory-Evoked Cortical Population Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
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- Modulation of cortical representations of sensory and contextual information underlies aversive associative learning.Cell reports · 2024Article
- Reward history guides focal attention in whisker somatosensory cortex.bioRxiv : the preprint server for biology · 2024Article
- Vagus nerve stimulation during training fails to improve learning in healthy rats.Scientific reports · 2024Article
- A transthalamic pathway crucial for perception.Nature communications · 2024Article
- Stimulus information guides the emergence of behavior-related signals in primary somatosensory cortex during learning.Cell reports · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurons in primary sensory cortex encode a variety of stimulus features upon perceptual learning. However, it is unclear whether the acquired stimulus selectivity remains stable when the same input is perceived in a different context. Here, we monitor the activity of individual neurons in the mouse primary somatosensory cortex during reward-based texture discrimination. We track their stimulus selectivity before and after changing reward contingencies, which allows us to identify various classes of neurons. We find neurons that stably represented a texture or the upcoming behavioral choice, but the majority is dynamic. Among those, a subpopulation of neurons regains texture selectivity contingent on the associated reward value. These value-sensitive neurons forecast the onset of learning by displaying a distinct and transient increase in activity, depending on past behavioral experience. Thus, stimulus selectivity of excitatory neurons during perceptual learning is dynamic and largely relies on behavioral contingencies, even in primary sensory cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.