Evidence map›Paper›PMID 32591490›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Lanell M Peterson, Brenda F Kurland, Fengting Yan, Alena Novakova- Jiresova, Vijayakrishna K Gadi, Jennifer M Specht, Julie R Gralow, Erin K Schubert, Jeanne M Link, Kenneth A Krohn and 3 more

Open access · bronzeAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Head-to-Head comparison of [European journal of nuclear medicine and molecular imaging · 2025
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Precision epigenetic therapies in oncology.Cancer metastasis reviews · 2025
    Review
  6. Article
  7. Article
  8. The Role of [Cancers · 2025
    Review
  9. [EJNMMI research · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  15. Review
  16. Novel applications of molecular imaging to guide breast cancer therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Review
  17. Review
  18. Review
  19. Review
  20. Novel Tracers and Radionuclides in PET Imaging.Radiologic clinics of North America · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Lanell M PetersonDivision of Medical Oncology, University of Washington/Seattle Cancer Care Alliance, Seattle, Washington.
Brenda F KurlandDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Fengting YanDivision of Medical Oncology, University of Washington/Seattle Cancer Care Alliance, Seattle, Washington.
Alena Novakova- JiresovaDepartment of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic.
Vijayakrishna K GadiDivision of Medical Oncology, University of Washington/Seattle Cancer Care Alliance, Seattle, Washington.
Jennifer M SpechtDivision of Medical Oncology, University of Washington/Seattle Cancer Care Alliance, Seattle, Washington.
Julie R GralowDivision of Medical Oncology, University of Washington/Seattle Cancer Care Alliance, Seattle, Washington.
Erin K SchubertDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Jeanne M LinkDepartment of Diagnostic Radiology, Oregon Health and Science University, Portland, Oregon; and.
Kenneth A KrohnDepartment of Diagnostic Radiology, Oregon Health and Science University, Portland, Oregon; and.
Janet F EaryCancer Imaging Program, National Cancer Institute, Bethesda, Maryland.
David A MankoffDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Hannah M LindenDivision of Medical Oncology, University of Washington/Seattle Cancer Care Alliance, Seattle, Washington hmlinden@uw.edu.
Seattle Cancer Care Alliance · USUniversity of Washington · USOregon Health & Science University · USUniversity of Pennsylvania · USNational Cancer Institute · USThomayer University Hospital · CZUniversity of Pittsburgh · US

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Robert H. Vonderheide · 1985 to 2026
$222.3M
VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
INSTITUTE FOR TRANSLATIONAL HEALTH SCIENCE (UL1): BPCAUL1RR025014 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$51.5M
RadiochemistryP01CA042045 · NCI · UNIVERSITY OF WASHINGTON · PI EARY, JANET F. · 1986 to 2015
$23.2M
TRAINING IN CANCER BIOLOGY &TRANSPLANTATIONT32CA009515 · NCI · UNIVERSITY OF WASHINGTON · PI NANCY ELLEN DAVIDSON, Effie W Petersdorf · 1985 to 2026
$16.2M
NCI NIH HHS P01 CA042045NCI NIH HHS P30 CA016520NCI NIH HHS P30 CA047904NCI NIH HHS T32 CA009515NCRR NIH HHS UL1 RR025014
6 · The paper itself

Abstract

Histone deacetylase inhibitors (HDACIs) may overcome endocrine resistance in estrogen receptor-positive (ER+) metastatic breast cancer. We tested whether

Indexed as

Positron-Emission TomographyAdultAgedBreast NeoplasmsErb-b2 Receptor Tyrosine KinasesEstradiolFemaleHumansImage Processing, Computer-AssistedMiddle AgedNeoplasm MetastasisReceptors, EstrogenVorinostat16-fluoroestradiolERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesEstradiolReceptors, EstrogenVorinostatER+ breast cancerestrogen receptorsFESmetastatic breast cancervorinostat

Identifiers

PMID32591490
PMCPMC9364869
OpenAlexW3037148349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.