Evidence map›Paper›PMID 32591392›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Cutting Edge: Augmenting Muscle MHC Expression Enhances Systemic Pathogen Control at the Expense of T Cell Exhaustion.

Angela D Pack, Rick L Tarleton

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Exhausted PD-1Frontiers in immunology · 2022
    Article
  6. The Blockade of Interleukin-2 During the Acute Phase ofFrontiers in cellular and infection microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Angela D PackDepartment of Microbiology, University of Georgia, Athens, GA 30602.ORCID 0000-0002-7579-2343
Rick L TarletonCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602; and tarleton@uga.edu.ORCID 0000-0002-9589-5243
University of Georgia · US

Funding

Training in Tropical and Emerging Global Diseases - SupplementT32AI060546 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI Silvia N Moreno, Vasant Muralidharan · 2004 to 2026
$5.1M
Trypanosoma cruzi dormancy and its implications for therapeutic treatmentR01AI151148 · NIAID · UNIVERSITY OF GEORGIA · PI TARLETON, RICK L · 2020 to 2024
$2.4M
Mechanisms of persistence in Trypanosoma cruzi infectionR01AI124692 · NIAID · UNIVERSITY OF GEORGIA · PI TARLETON, RICK L · 2016 to 2020
$1.9M
Transmission-blocking live vaccine for Chagas diseaseR01AI089952 · NIAID · UNIVERSITY OF GEORGIA · PI TARLETON, RICK L · 2012 to 2016
$1.8M
NIAID NIH HHS R01 AI089952NIAID NIH HHS R01 AI124692NIAID NIH HHS R01 AI151148NIAID NIH HHS T32 AI060546
6 · The paper itself

Abstract

Myocytes express low levels of MHC class I (MHC I), perhaps influencing the ability of CD8

Indexed as

AnimalsB7-H1 AntigenCD8-Positive T-LymphocytesChagas DiseaseGene Expression RegulationHistocompatibility Antigens Class IMiceMice, TransgenicMuscle Fibers, SkeletalProgrammed Cell Death 1 ReceptorTrypanosoma cruziB7-H1 AntigenCd274 protein, mouseHistocompatibility Antigens Class IPdcd1 protein, mouseProgrammed Cell Death 1 Receptor

Identifiers

PMID32591392
PMCPMC7369248
OpenAlexW3038104782

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.