Evidence map›Paper›PMID 32591185›Full record

ArticleRevista espanola de anestesiologia y reanimacion

SEDAR-SEMICYUC consensus recommendations on the management of haemostasis disorders in severely ill patients with COVID-19 infection.

J V Llau, R Ferrandis, P Sierra, F Hidalgo, C Cassinello, A Gómez-Luque, M Quintana, R Amezaga, M Gero, A Serrano and 1 more

Registry-linked trialOpen access · greenAbstract readConsensus Statement
In one paragraph

Article in Revista espanola de anestesiologia y reanimacion. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04623177 (Effectiveness of Thromboprophylaxis With Low Molecular Weight Heparin in Critically Ill Patients With COVID-19. A Prospective, Cohort, Multicenter Study.), which is not on this map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04623177 completednot on this map

Effectiveness of Thromboprophylaxis With Low Molecular Weight Heparin in Critically Ill Patients With COVID-19. A Prospective, Cohort, Multicenter Study.

TypeobservationalSponsorInstituto de Investigacion Sanitaria La FeRan2020 to 2020Enrolled822ConditionsCovid19, Anticoagulant Therapy, Thrombosis
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. [Post-COVID syndrome: A reflection and opinion paper].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Review
  8. Article
  9. Venous Thromboembolism in COVID-19.Thrombosis and haemostasis · 2020
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 11 institutions in 1 country.

J V LlauServicio de Anestesiología-Reanimación y Terapéutica del Dolor, Hospital Universitari Doctor Peset, SEDAR, Valencia, España. Electronic address: juanvllau@gmail.com.
R FerrandisServicio de Anestesiología-Reanimación y Terapéutica del Dolor, Hospital Universitari i Politècnic La Fe, SEDAR, Valencia, España.
P SierraServicio de Anestesiología-Reanimación y Terapéutica del Dolor, Fundació Puigvert, SEDAR , Barcelona, España.
F HidalgoServicio de Anestesiología-Reanimación y Terapéutica del Dolor, Clínica Universidad de Navarra, SEDAR, Pamplona, Navarra, España.
C CassinelloServicio de Anestesiología-Reanimación y Terapéutica del Dolor, Hospital Universitario Miguel Servet, SEDAR, Zaragoza, España.
A Gómez-LuqueServicio de Anestesiología-Reanimación y Terapéutica del Dolor, Hospital Universitario Virgen de la Victoria, SEDAR, Málaga, España.
M QuintanaServicio de Medicina Intensiva, Hospital Universitario La Paz-Carlos III, SEMICYUC, Madrid, España.
R AmezagaServicio de Medicina Intensiva, Hospital Universitario Son Espases, SEMICYUC, Palma de Mallorca, Baleares, España.
M GeroServicio de Medicina Intensiva, Hospital Universitario, SEMICYUC, Burgos, España.
A SerranoServicio de Medicina Intensiva, Hospital Clínico Universitario, SEMICYUC, Valencia, España.
P MarcosServicio de Medicina Intensiva, Hospital Germans Trias i Pujol, SEMICYUC, Badalona, Barcelona, España.
Clinica Universidad de Navarra · ESHospital Clínico Universitario de Valencia · ESHospital Clínico Universitario Virgen de la Victoria · ESHospital Universitari Germans Trias i Pujol · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario de Burgos · ESHospital Universitario Doctor Peset · ESHospital Universitario La Paz · ESHospital Universitario Miguel Servet · ESHospital Universitario Son Espases · ESPuigvert Foundation · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The infection by the coronavirus SARS-CoV-2, which causes the disease called COVID-19, mainly causes alterations in the respiratory system. In severely ill patients, the disease often evolves into an acute respiratory distress syndrome that can predispose patients to a state of hypercoagulability, with thrombosis at both venous and arterial levels. This predisposition presents a multifactorial physiopathology, related to hypoxia as well as to the severe inflammatory process linked to this pathology, including the additional thrombotic factors present in many of the patients. In view of the need to optimise the management of hypercoagulability, the working groups of the Scientific Societies of Anaesthesiology-Resuscitation and Pain Therapy (SEDAR) and of Intensive, Critical Care Medicine and Coronary Units (SEMICYUC) have developed a consensus to establish guidelines for actions to be taken against alterations in haemostasis observed in severely ill patients with COVID-19. These recommendations include prophylaxis of venous thromboembolic disease in these patients, and in the peripartum, management of patients on long-term antiplatelet or anticoagulant treatment, bleeding complications in the course of the disease, and the interpretation of general alterations in haemostasis.

Indexed as

BetacoronavirusAnticoagulantsBlood Coagulation DisordersCoronavirus InfectionsCOVID-19FemaleHemorrhageHumansPandemicsPlatelet Aggregation InhibitorsPneumonia, ViralPregnancyPregnancy Complications, HematologicPregnancy Complications, InfectiousSARS-CoV-2ThromboembolismAnticoagulantsPlatelet Aggregation InhibitorsAnticoagulantesAnticoagulantsAnti-plateletsAntitrombóticosComplicaciones del embarazoCoronavirus infectionsCOVID-19Heparina de bajo peso molecularInfecciones por coronavirusLow-molecular-weight heparinPregnancy complicationsThrombosisTrombosis

Identifiers

PMID32591185
PMCPMC7245242
OpenAlexW3028217092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.